Thiourea inhibitors of herpes viruses. Part 2: N-Benzyl-N′- arylthiourea inhibitors of CMV
A series of highly potent thiourea inhibitors of cytomegalovirus (CMV) with improved stability properties was prepared and evaluated. Compound 29 inhibited the virus in cultured HFF cells with IC50 of 0.2nM.
Bloom, Jonathan D.,Dushin, Russell G.,Curran, Kevin J.,Donahue, Fran,Norton, Emily B.,Terefenko, Eugene,Jones, Thomas R.,Ross, Adma A.,Feld, Boris,Lang, Stanley A.,DiGrandi, Martin J.
p. 3401 - 3406
(2007/10/03)
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