- Steering On-Surface Reactions by a Self-Assembly Approach
-
4,4′-Bis(2,6-difluoropyridin-4-yl)-1,1′:4′,1′′-terphenyl (BDFPTP) molecules underwent dehydrocyclization and covalent coupling reactions on Au(111) according to scanning tunneling microscopy (STM) measurements and density functional theory (DFT) calculati
- Chen, Qiwei,Cramer, Jacob R.,Liu, Jing,Jin, Xin,Liao, Peilin,Shao, Xiang,Gothelf, Kurt V.,Wu, Kai
-
-
Read Online
- Pinning-down molecules in their self-assemblies with multiple weak hydrogen bonds of C[sbnd]H?F and C[sbnd]H?N
-
Two-dimensional self-assemblies of four partially fluorinated molecules, 1,4-bis(2,6-difluoropyridin-4-yl)benzene, 4,4′-bis(2,6-difluoropyridin-4-yl)-1,1′-biphenyl, 4,4′-bis(2,6-difluoropyridin-4-yl)-1,1′:4′,1″-terphenyl and 4,4′-bis(2,6-difluoropyridin-3-yl)-1,1′-biphenyl, involving weak intermolecular C[sbnd]H?F and C[sbnd]H?N hydrogen bonds were systematically investigated on Au(111) with low-temperature scanning tunneling microscopy. The inter-molecular connecting modes and binding sites were closely related to the backbones of the building blocks, i.e., the molecule length determines its binding sites with neighboring molecules in the assemblies while the attaching positions of the N and F atoms dictate its approaching and docking angles. The experimental results demonstrate that multiple weak hydrogen bonds such as C[sbnd]H?F and C[sbnd]H?N can be efficiently applied to tune the molecular orientations and the self-assembly structures accordingly.
- Jin, Xin,Cramer, Jacob R.,Chen, Qi-Wei,Liang, Hai-Lin,Shang, Jian,Shao, Xiang,Chen, Wei,Xu, Guo-Qin,Gothelf, Kurt V.,Wu, Kai
-
p. 525 - 530
(2017/06/19)
-
- Synthetic entries to substituted bicyclic pyridones
-
(Chemical Equation Presented) The synthesis of 6,6- and 5,6-bicyclic pyridone scaffolds has been completed using (i) an intramolecular Mitsunobu reaction and/or (ii) hydrolysis of a bicyclic pyridinium salt intermediate. Regioselective functionalization o
- Cheng, Dachen,Croft, Laura,Abdi, Muna,Lightfoot, Andrew,Gallagher, Timothy
-
p. 5175 - 5178
(2008/09/17)
-
- The structural proliferation of 2,6-difluoropyridine through organometallic intermediates
-
Contrary to a literature claim, 2,6-difluoropyridine-3-carboxaldehyde can be readily prepared by consecutive treatment of 2,6-difluoropyridine with lithium diisopropylamide and N,N-dimethylformamide. Regioselective displacements of fluorine from the aldehyde by nucleophiles were carried out. To demonstrate the versatility of the organometallic approach, some two dozens of further 2,6-difluoropyridine derivatives were prepared applying a combination of modern organometallic methods such as site selective hydrogen/metal and halogen/metal permutations and deprotonation-triggered heavy halogen migrations. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004.
- Schlosser, Manfred,Rausis, Thierry
-
p. 1018 - 1024
(2007/10/03)
-