69045-85-8

Basic information

• Product Name: 4-{[5-(TRIFLUOROMETHYL)PYRIDIN-2-YL]OXY}PHENOL
• Synonyms: 4-{[5-(TRIFLUOROMETHYL)PYRIDIN-2-YL]OXY}PHENOL;4-[[5-(Trifluoromethyl)-2-pyridyl]oxy]phenol
• CAS NO: 69045-85-8
• Molecular Formula: C₁₂H₈F₃NO₂
• Molecular Weight: 255.1926296
• Mol File: 69045-85-8.mol

Chemical Properties

• Boiling Point: 341.9°C at 760 mmHg
• Flash Point: 160.6°C
• Appearance: /
• Density: 1.378g/cm³
• Vapor Pressure: 3.94E-05mmHg at 25°C
• Refractive Index: 1.534
• Storage Temp.: -20°C Freezer, Under inert atmosphere
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• CAS DataBase Reference: 4-{[5-(TRIFLUOROMETHYL)PYRIDIN-2-YL]OXY}PHENOL(CAS DataBase Reference)
• NIST Chemistry Reference: 4-{[5-(TRIFLUOROMETHYL)PYRIDIN-2-YL]OXY}PHENOL(69045-85-8)
• EPA Substance Registry System: 4-{[5-(TRIFLUOROMETHYL)PYRIDIN-2-YL]OXY}PHENOL(69045-85-8)

Safety Data

• Hazardous Substances Data: 69045-85-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C12H8F3NO2/c13-12(14,15)8-1-6-11(16-7-8)18-10-4-2-9(17)3-5-10/h1-7,17H

Upstream product

• 52334-81-3 2-chloro-5-trifluoromethylpyridine 
• 123-31-9 hydroquinone 
• 108-95-2 phenol 
• 69045-86-9 5-(trifluoromethyl)-2-(4-methoxyphenoxy)pyridine 

Downstream Products

• 549510-44-3 4-Phenyl-piperazine-1-carboxylic acid 4-(5-trifluoromethyl-pyridin-2-yloxy)-phenyl ester 
• 549512-05-2 4-(Isopropylaminocarbonylmethyl)-piperazine-1-carboxylic acid 4-(5-trifluoromethyl-pyridin-2-yloxy)-phenyl ester 
• 549510-43-2 4-(2-Hydroxyethyl)-piperazine-1-carboxylic acid 4-(5-trifluoromethyl-pyridin-2-yloxy)-phenyl ester 
• 548766-20-7 4-Carbamoyl-piperidine-1-carboxylic acid 4-(5-trifluoromethyl-pyridin-2-yloxy)-phenyl ester 
• 548766-18-3 4-(2-Oxo-2,3-dihydro-benzimidazol-1-yl)-piperidine-1-carboxylic acid 4-(5-trifluoromethyl-pyridin-2-yloxy)-phenyl ester 
• 722454-19-5 4-(Pyrrolidinocarbonylmethyl)-piperazine-1-carboxylic acid 4-(5-trifluoromethyl-pyridin-2-yloxy)-phenyl ester 
• 548766-19-4 3-Diethylcarbamoyl-piperidine-1-carboxylic acid 4-(5-trifluoromethyl-pyridin-2-yloxy)-phenyl ester 
• 548766-21-8 3-Carbamoyl-piperidine-1-carboxylic acid 4-(5-trifluoromethyl-pyridin-2-yloxy)-phenyl ester 
• 549510-42-1 4-Benzyl-piperazine-1-carboxylic acid 4-(5-trifluoromethyl-pyridin-2-yloxy)-phenyl ester 
• 69335-91-7 fluazifop 
• 106372-22-9 2-[4-(5-trifluoromethyl-2-pyridyloxy)-phenoxy] propionic acid (N-methoxy-N-methyl-aminocarbonyl) methyl ester 
• 72584-04-4 2-[4-[[5-(trifluoromethyl)-2-pyridyl]oxy]phenoxy]propan-1-ol 
• 109231-32-5 2-[4-[[5-(trifluoromethyl)-2-pyridyl]oxy]phenoxy]propanal 
• 72584-06-6 2-[4-[[5-(trifluoromethyl)-2-pyridyl]oxy]phenoxy]propyl acetate 

Relevant articles and documents

A process for preparing 4 - substituted oxy phenol compounds

The invention belongs to the field of organic synthesis, and relates to a method for preparing a 4-substituted oxyphenol compound. The method comprising the following steps: condensing hydroquinone and a halogen compound in a polar aprotic solvent in a reducing agent and metal alkali system to obtain the 4-substituted oxyphenol compound; removing the solvent after the above reaction, adding a non-polar solvent, filtering, washing, and recovering the raw material hydroquinone; and washing the obtained filtrate through using water, extracting by using an alkaline solution, and adjusting the pH value of the obtained extract solution to obtain the 4-substituted oxyphenol compound. The method has the advantages of short route, simple operation, high selectivity, high yield, good atom economy, high product content, recovery convenience and recycling of the raw material, reduction of three wastes and the cost, and suitableness for industrial production.

Design, synthesis and insecticidal evaluation of aryloxy dihalopropene derivatives

Plutella xylostella (P. xylostella) is a highly migratory, cosmopolitan species and one of the most important pest of cruciferous crops worldwide. Pyridalyl as a novel class of insecticides has good efficacy against P. xylostella. On the basis of the commercial insecticide pyridalyl, a series of new aryloxy dihalopropene derivatives were designed and synthesized by using Intermediate Derivatization Methods. Their chemical structures were confirmed by 1H NMR, high-resolution mass spectrum (HRMS), and single-crystal X-ray diffraction analysis. The insecticidal activities of the new compounds against P. xylostella were evaluated. The results of bioassays indicated that most of the compounds showed moderate to high activities at the tested concentration, especially compounds 10e and 10g displayed more than 75% insecticidal activity against P. xylostella at 6.25 mg/L, while pyridalyl showed 50% insecticidal activity at the same concentration. The field trials result of the insecticidal activities showed that compound 10e as a 10% emulsifiable concentrate (EC) was effective in the control of P. xylostella at 75-150 g a.i./ha, and the mortality of P. xylostella for treatment with compound 10e at 75 g a.i./ha was equivalent to pyridalyl at 105 g a.i./ha.

ARYLOXY DIHALOPROPENYL ETHER COMPOUNDS AND USES THEREOF

The present invention discloses an aryloxy dihalopropenyl ether compound with the structure shown as general formula (I), of which the group definitions can be seen in the specification. The present invention also discloses the use of the compound with ge

Evaluation of the Elbs Persulfate Oxidation Reaction for the Preparation of Aryloxyphenoxypropionate Herbicides

A new, simple method for the preparation of several 4-(aryloxy)phenols (2a-d) and alkyl 2-(4-hydroxyphenoxy)propionates (3a,b) is described.These compounds are key precursors for the synthesis of important aryloxyphenoxypropionate herbicides (1a-d).The method uses the Elbs persulfate oxidation to convert phenol into 4-hydroxyphenyl sulfate (5).The free hydroxy group is then reacted with various aryl halides and alkyl 2-halopropionates.Mild hydrolysis of the sulfate group with boiling acetic acid then gives the products (2a-d) and (3a,b), generally in modest to good yield.

Selective cleavage of aryl methyl ether moiety of aryloxy aryl methyl ether by 48% HBr/tetra-n-butylphosphonium bromide

Aryl methyl ether moiety in the molecule containing aryl aryl ether part along with aryl methyl ether part is selectively cleaved to give the desired substituted phenol in excellent yield by using 48% HBr in the presence of tetra-n-butylphosphonium bromid

Substituted phenoxypropionates and herbicidal compositions containing same and their herbicidal use

Novel substituted phenoxypropionates of the formula STR1 in which Ar represents the group STR2 or the group STR3 in which Y represents a halogen atom or a trifluoromethyl group and b is 1 or 2, R represents a hydrogen atom or a methyl group, X represents

Herbicidal pyridine compounds

Herbicidal 3- and/or 5-halogenomethyl-pyrid-2-yloxyphenoxy compounds and processes for making and using the same. Intermediates for making these compounds and their preparation are also disclosed. Thus, for example, 2-chloro-5-trichloromethylpyridine is prepared by a liquid phase chlorination of 3-methylpyridine under the influence of ultra violet light.

Process for preparing substituted pyridinyloxy ether intermediate

A process for preparing pyridinyloxyphenols, useful intermediates in preparing pyridyloxyphenyl ether herbicides, in which a halopyridine is heated with hydroquinone in the absence of base and, optionally, in the absence of solvent.

4-[4-(5-Trifluoromethyl-2-pyridyloxy)phenoxy]-2-pentenoic acid esters useful as a herbicide

4-[4-(5-Trifluoromethyl-2-pyridyloxy)phenoxy]-2-pentenoic acid esters, a herbicidal composition containing the same, and a method of controlling weeds using the same.

2-Phenoxy-5-trifluoromethylpyridine compounds and process for preparation thereof

A 2-phenoxy-5-trifluoromethylpyridine compound represented by the following general formula (I): STR1 wherein X represents a hydrogen atom or a chlorine atom, and R represents a hydrogen atom or a cation, and a process for the preparation thereof.