69103-75-9

Basic information

• Product Name: methyl acetylphosphonate
• CAS NO: 69103-75-9
• Molecular Formula: C₃H₆O₄P*Na
• Molecular Weight: 0
• Mol File: 69103-75-9.mol

Chemical Properties

• Boiling Point: 222.6°C at 760 mmHg
• Flash Point: 88.4°C
• Appearance: /
• Vapor Pressure: 0.0374mmHg at 25°C
• CAS DataBase Reference: methyl acetylphosphonate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl acetylphosphonate(69103-75-9)
• EPA Substance Registry System: methyl acetylphosphonate(69103-75-9)

Safety Data

• Hazardous Substances Data: 69103-75-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C3H7O4P.Na/c1-3(4)8(5,6)7-2;/h1-2H3,(H,5,6);/q;+1/p-1

Upstream product

• 17674-28-1 dimethyl acetylphosphonate 
• 75-36-5 acetyl chloride 
• 121-45-9 phosphorous acid trimethyl ester 

Downstream Products

• 877-95-2 methyl-N-(benzyl-methyl)-formamide 

Relevant articles and documents

Alkyl and aryl α-ketophosphonate derivatives as photoactive compounds targeting glutathione S-transferases

In this article, photoactive alkyl and aryl α-ketophosphonate derivatives were studied as inhibitors of glutathione S-transferases (GSTs). The α-ketophosphonate monoesters were synthesized by sodium iodide-induced dealkylation of corresponding phosphonate

Acylphosphonic acids and methyl hydrogen acylphosphonates: Physical and chemical properties and theoretical calculations

Acylphosphonic acids (5) and methyl hydrogen acylphosphonates (3) were synthesized by di- and mono-demethylation of dimethyl acylphosphonates (1). Spectroscopic data (i.r., 31P and 1H n.m.r.) are reported for these types of compounds for the first time. Examination of their hydrolytic stability under acidic and basic conditions revealed that except for methyl hydrogen acylphosphonates (3) that are unstable under highly alkaline pH conditions, the C-P bond in these types of compounds is stable in most cases. Nucleophilic reagents, e.g. amines, borohydride, or hydroxylamine react with the carbonyl group of ionized acylphosphonates with the preservation of the C-P bond, to yield α-imino-, α-hydroxy-, or α-oxyimino- alkylphosphononate anions, respectively. Semi-empirical quantum mechanical (MNDO/H) calculations were performed on benzoylphosphonic acid (5c) and on the esters and anions derived from it, as representatives of their classes, in order to assess bond lengths and preferred conformations, and to estimate charges on the carbonyl and phosphoryl groups. Calculations show that for both neutral and ionized (anions) compounds free rotation around the C-P bond is expected due to the low energy barriers.

Compounds and compositions

There are described pesticidal compositions comprising one or more compounds of the formula I, STR1 in which Ra is a group R2 or --OR2, E is oxygen or sulphur, Rm is --O? M≈ or --NRyRz, M≈ is one equi