69316-09-2

Basic information

• Product Name: 3-(3,5-dichlorophenyl)-3-oxopropanenitrile
• Synonyms: 3-(3,5-dichlorophenyl)-3-oxopropanenitrile;UKRORGSYN-BB BBV-073763
• CAS NO: 69316-09-2
• Molecular Formula: C₉H₅Cl₂NO
• Molecular Weight: 214.05
• Mol File: 69316-09-2.mol

Chemical Properties

• Boiling Point: 393.3°C at 760 mmHg
• Flash Point: 191.7°C
• Appearance: /
• Density: 1.383g/cm³
• Vapor Pressure: 2.15E-06mmHg at 25°C
• Refractive Index: 1.567
• CAS DataBase Reference: 3-(3,5-dichlorophenyl)-3-oxopropanenitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(3,5-dichlorophenyl)-3-oxopropanenitrile(69316-09-2)
• EPA Substance Registry System: 3-(3,5-dichlorophenyl)-3-oxopropanenitrile(69316-09-2)

Safety Data

• Hazardous Substances Data: 69316-09-2(Hazardous Substances Data)

Usage

Uses

Used in Agricultural Applications:
Fenvalerate is used as an insecticide in agriculture for controlling a wide range of pests, including mosquitoes, flies, cockroaches, and ants. Its effectiveness in targeting various insects makes it a valuable tool in protecting crops and maintaining agricultural productivity.
Used in Household Pest Control:
Fenvalerate is also used in household settings as an insecticide to eliminate pests that can cause discomfort and health issues. Its broad-spectrum action allows for effective control of common household insects, contributing to a cleaner and healthier living environment.
Used in Combination with Other Insecticides:
Fenvalerate is often used in combination with other insecticides to enhance its efficacy and broaden the range of pests it can target. This synergistic approach allows for more effective pest control and helps in managing resistance development in insect populations.
Used in Various Formulations:
Fenvalerate is available in different formulations, such as sprays, dusts, and emulsifiable concentrates, to suit various application methods and target different types of pests. This versatility in formulation allows for tailored pest control solutions based on specific needs and situations.
Caution in Aquatic Environments:
Due to its high toxicity to fish and other aquatic organisms, fenvalerate should be used with caution near water sources to prevent harm to aquatic ecosystems. Proper handling and application practices are essential to minimize environmental impact.

InChI:InChI=1/C9H5Cl2NO/c10-7-3-6(4-8(11)5-7)9(13)1-2-12/h3-5H,1H2

Upstream product

• 91085-56-2 3,5-dichlorobenzoic acid ethyl ester 
• 75-05-8 acetonitrile 
• 18293-53-3 2-trimethylsilylacetonitrile 
• 3032-81-3 3,5-dichloroiodobenzene 
• 13939-06-5 molybdenum hexacarbonyl 

Downstream Products

• 69316-22-9 3-(3,5-Dichlor-phenyl)-2-oximino-3-oxo-propionitril 
• 92406-45-6 5-(3,5-Dichloro-phenyl)-2-methyl-2H-pyrazol-3-ylamine 
• 92406-26-3 methyl 3-(3,5-dichlorophenyl)-1,6-dimethyl-4-(3-nitrophenyl)-4,7-dihydropyrazolo[3,4-b]pyridine-5-carboxylate 
• 907190-89-0 3-(3,5-dichlorophenyl)-1-(2-naphthyl)-1H-pyrazol-5-amine 
• 1195951-29-1 C₁₆H₁₀Cl₂F₃N₃O 
• 766520-00-7 5-(3,5-dichloro-phenyl)-2H-pyrazol-3-ylamine 
• 1441962-06-6 2-amino-6-(3-chlorophenyl)-4-(3,5-dichlorophenyl)-pyrimidine-5-carbonitrile 
• 1195951-92-8 C₃₁H₂₉Cl₂F₃N₄O₄ 
• 1195951-93-9 C₂₇H₂₁Cl₂F₃N₄O₄ 
• 1195951-36-0 C₃₁H₂₉Cl₂F₃N₄O₄ 
• 1195951-37-1 C₂₇H₂₁Cl₂F₃N₄O₄ 
• 1195951-33-7 C₂₆H₁₉Cl₂F₃N₄O₄ 
• 1195951-34-8 C₂₄H₁₅Cl₂F₃N₈O₂ 
• 1195951-35-9 C₂₈H₂₄Cl₂F₃N₃O₃ 

Relevant articles and documents

One-pot synthesis of benzoylacetonitriles through sequential Pd-catalyzed carbonylation and decarboxylation

Benzoylacetonitrile were prepared through sequential carbonylation and decarboxylation. The palladium-catalyzed carbonylation of aryl iodides and methyl cyanoacetate using Mo(CO)6 as a carbon monoxide source afforded beta-keto cyanoesters, and then the subsequent reaction with Li/H2O produced the desired benzoylacetonitriles.

Palladium-catalyzed carbonylation with Mo(CO)for the synthesis of benzoylacetonitriles

Benzoylacetonitriles were synthesized by the palladium-catalyzed carbonylation of aryl iodides and trimethylsilylacetonitrile using Mo(CO)as a carbon monoxide source. Pd(PPhCland CuFwere employed as the catalyst and activator, respectively. A variety of aryl iodides bearing alkyl, alkoxy, fluoro, chloro, bromo, nitrile, ester, and ketone groups afforded the corresponding benzoylacetonitriles in moderate to good yields. Georg Thieme Verlag Stuttgart ? New York.

Design, synthesis, and evaluation of 2-aryl-7-(3′,4′-dialkoxyphenyl)-pyrazolo[1,5-a]pyrimidines as novel PDE-4 inhibitors

Described herein is design, synthesis, and biological evaluation of novel series of 2-aryl-7-(3′,4′-dialkoxyphenyl)-pyrazolo[1,5-a]pyrimidines acting as inhibitors of type 4 phosphodiesterase (PDE4) which is known as a good target for the treatment of asthma and COPD. For this purpose, structure optimization was conducted with the aid of structure-based drug design using the known X-ray crystallography. Also, biological effects of these compounds on the target enzyme were evaluated by using in vitro assays, leading to the potent and selective PDE-4 inhibitor (IC50 10 nM).