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7-BMAC, or 7-Bromo-8-hydroxy-3-methylisochroman-1-one, is a synthetic compound that serves as a selective agonist in scientific research. It is primarily used to stimulate specific receptors, particularly the metabotropic glutamate receptor mGlu1. 7-BMAC is instrumental in research aimed at developing treatments for conditions related to memory and perception defects, as it modulates the activity of glutamate receptors in the brain. 7-BMAC is a promising candidate for the development of effective treatments for neurological disorders such as Alzheimer's and Parkinson's.

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  • Factory Supply diphenylmethyl (6R,7S)-7-[(bromoacetyl)amino]-7-methoxy-3-{[(1-methyl-1H-tetrazol-5-yl)thio]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

    Cas No: 70035-75-5

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  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[(2-bromoacetyl)amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-,diphenylmethyl ester, (6R,7S)-

    Cas No: 70035-75-5

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  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[(2-bromoacetyl)amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-,diphenylmethyl ester, (6R,7S)-

    Cas No: 70035-75-5

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  • 70035-75-5 Structure
  • Basic information

    1. Product Name: 7-BMAC
    2. Synonyms: 7-BMAC;(6R,7S)-7-[(Bromoacetyl)amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid diphenylmethyl ester;(6R,7S)-7-[(BroMoacetyl)aMino]-7-Methoxy-3-[[(1-Methyl-1H-tetrazol-5-yl)thio]Methyl]-8-oxo-5-thia-1-
    3. CAS NO:70035-75-5
    4. Molecular Formula: C26H25BrN6O5S2
    5. Molecular Weight: 645.55
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 70035-75-5.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.62
    6. Refractive Index: 1.726
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 7-BMAC(CAS DataBase Reference)
    10. NIST Chemistry Reference: 7-BMAC(70035-75-5)
    11. EPA Substance Registry System: 7-BMAC(70035-75-5)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 70035-75-5(Hazardous Substances Data)

70035-75-5 Usage

Uses

Used in Pharmaceutical Research:
7-BMAC is used as a research compound for the development of treatments targeting memory and perception defects. Its agonistic action on the metabotropic glutamate receptor mGlu1 makes it a valuable tool in understanding the underlying mechanisms of neurological conditions and exploring potential therapeutic interventions.
Used in Neurological Condition Treatments:
7-BMAC is used as a potential therapeutic agent for neurological conditions such as Alzheimer's and Parkinson's. Its ability to control and alter the activity of glutamate receptors in the brain suggests that it could play a role in managing the symptoms and progression of these disorders, offering hope for more effective treatments in the future.

Check Digit Verification of cas no

The CAS Registry Mumber 70035-75-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,0,0,3 and 5 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 70035-75:
(7*7)+(6*0)+(5*0)+(4*3)+(3*5)+(2*7)+(1*5)=95
95 % 10 = 5
So 70035-75-5 is a valid CAS Registry Number.
InChI:InChI=1/C26H25BrN6O5S2/c1-32-25(29-30-31-32)40-15-18-14-39-24-26(37-2,28-19(34)13-27)23(36)33(24)20(18)22(35)38-21(16-9-5-3-6-10-16)17-11-7-4-8-12-17/h3-12,21,24H,13-15H2,1-2H3,(H,28,34)/t24-,26+/m1/s1

70035-75-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name benzhydryl (6R,7S)-7-[(2-bromoacetyl)amino]-7-methoxy-8-oxo-3-[1-(2H-tetrazol-5-ylsulfanyl)ethyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

1.2 Other means of identification

Product number -
Other names C.I. Acid blue 5

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

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Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:70035-75-5 SDS

70035-75-5Relevant articles and documents

Preparation method of cefotetan disodium

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Paragraph 0017, (2018/04/01)

The invention discloses a preparation method of cefotetan disodium, comprising the following steps: (1) preparing a first intermediate; (2) separating by extraction; (3) preparing a second intermediate; (4) separating by crystallization; (5) preparing a c

Purification of béta-lactam products

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Page/Page column 2, (2010/11/26)

Method for purifying 7α-methoxy-cephalosporins containing as impurity the corresponding 7α-methylthio analogue, which is transformed into its methoxy analogue by treatment with a halogenating agent in methanol.

PURIFICATION OF BETA-LACTAM PRODUCTS

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Page/Page column 1-2, (2008/06/13)

Method for purifying 7α-methoxy-cephalosporins containing as impurity the corresponding 7α-methylthio analogue, which is transformed into its methoxy analogue by treatment with a halogenating agent in methanol. In this way the complete conversion of the s

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