Welcome to LookChem.com Sign In|Join Free

CAS

  • or
4-CHLORO-2-IODOTHIENO[2,3-B]PYRIDINE-5-CARBONITRILE is a heterocyclic chemical compound with the molecular formula C7H2ClIN2S. It features a thiophene ring fused to a pyridine ring, with chlorine and iodine atoms attached to the thiophene ring at positions 4 and 2, respectively. The presence of a cyano group at position 5 of the pyridine ring classifies it as a carbonitrile compound. 4-CHLORO-2-IODOTHIENO[2,3-B]PYRIDINE-5-CARBONITRILE is utilized in the synthesis of pharmaceuticals and agrochemicals and may serve as a building block in organic chemistry. Its specific applications and properties are under continuous research and development within the chemical sciences field.

700844-18-4 Suppliers

Post Buying Request

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier
  • 700844-18-4 Structure
  • Basic information

    1. Product Name: 4-CHLORO-2-IODOTHIENO[2,3-B]PYRIDINE-5-CARBONITRILE
    2. Synonyms: 4-CHLORO-2-IODOTHIENO[2,3-B]PYRIDINE-5-CARBONITRILE
    3. CAS NO:700844-18-4
    4. Molecular Formula: C8H2ClIN2S
    5. Molecular Weight: 320.53735
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 700844-18-4.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 429.985 °C at 760 mmHg
    3. Flash Point: 213.848 °C
    4. Appearance: /
    5. Density: 2.166 g/cm3
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C
    8. Solubility: N/A
    9. CAS DataBase Reference: 4-CHLORO-2-IODOTHIENO[2,3-B]PYRIDINE-5-CARBONITRILE(CAS DataBase Reference)
    10. NIST Chemistry Reference: 4-CHLORO-2-IODOTHIENO[2,3-B]PYRIDINE-5-CARBONITRILE(700844-18-4)
    11. EPA Substance Registry System: 4-CHLORO-2-IODOTHIENO[2,3-B]PYRIDINE-5-CARBONITRILE(700844-18-4)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 700844-18-4(Hazardous Substances Data)

700844-18-4 Usage

Uses

Used in Pharmaceutical Synthesis:
4-CHLORO-2-IODOTHIENO[2,3-B]PYRIDINE-5-CARBONITRILE is used as an intermediate in the synthesis of pharmaceuticals for its unique structural features that can be further modified to create new drug molecules.
Used in Agrochemical Synthesis:
In the agrochemical industry, 4-CHLORO-2-IODOTHIENO[2,3-B]PYRIDINE-5-CARBONITRILE is used as a precursor in the development of new agrochemicals, potentially leading to more effective and targeted pest control solutions.
Used in Organic Chemistry as a Building Block:
4-CHLORO-2-IODOTHIENO[2,3-B]PYRIDINE-5-CARBONITRILE is utilized as a building block in organic chemistry, allowing chemists to explore its reactivity and potential for creating novel compounds with various applications.

Check Digit Verification of cas no

The CAS Registry Mumber 700844-18-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,0,0,8,4 and 4 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 700844-18:
(8*7)+(7*0)+(6*0)+(5*8)+(4*4)+(3*4)+(2*1)+(1*8)=134
134 % 10 = 4
So 700844-18-4 is a valid CAS Registry Number.

700844-18-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-CHLORO-2-IODOTHIENO[2,3-B]PYRIDINE-5-CARBONITRILE

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:700844-18-4 SDS

700844-18-4Relevant articles and documents

A facile, scalable preparation of 4-oxo-4,7-dihydrothieno[2,3-b]pyridine-5-carbonitriles

Tumey, L. Nathan,Bhagirath, Niala,Wu, Biqi,Boschelli, Diane H.

scheme or table, p. 6850 - 6852 (2009/04/07)

We report a new synthesis of thieno[2,3-b]pyridine-5-carbonitriles from 2-aminothiophene-3-carboxylate esters. The key step of the synthesis is a thermally promoted elimination/decarboxylation followed by nucleophilic cyclization to give 4-oxo-4,7-dihydrothieno[2,3-b]pyridine-5-carbonitriles. The reactions proceed in good yield and generally require no chromatographic purification. These compounds are easily transformed in two steps to 4-chloro-2-iodothieno[2,3-b]pyridine-5-carbonitriles which are key intermediates in the synthesis of various kinase inhibitors.

Process for the preparation of 4-hydroxythieno[2,3-b]pyridine-5-carbonitriles

-

Page/Page column 16, (2008/06/13)

A process for the preparation of 4-hydroxythieno[2,3-b]pyridine-5-carbonitriles, which can be useful for the preparation of protein kinase inhibitors, is provided.

Identification of 7-phenylaminothieno-[3,2-b]pyridine-6-carbonitriles as a new class of Src kinase inhibitors

Boschelli, Diane H.,Wu, Biqi,Sosa, Ana Carolina Barrios,Durutlic, Haris,Ye, Fei,Raifeld, Yuri,Golas, Jennifer M.,Boschelli, Frank

, p. 6666 - 6668 (2007/10/03)

We disclose here a new class of kinase inhibitors, obtained by replacing the phenyl ring of a 3-quinolinecarbonitrile system with a thiophene ring. When suitably substituted, the resultant 7-phenylaminothieno[3,2-b]pyridine-6- carbonitrile analogues show

Thieno[3,2-b]pyridine-6-carbonitriles and thieno[2,3-b]pyridine-5-carbonitriles as protein kinase inhibitors

-

, (2008/06/13)

This invention provides compounds of Formula (1a)-(1f), II wherein: X, m, n, q, R1, R2, R3, R4, R5, R6, R7, R8, R9, Y, Q, Z, Z′, Z′″, Z″ and J are defined hereinbefore in the specification, which are useful in the treatment of cancer, stroke, myocardial infarction, neuropathic pain, osteoporosis, polycystic kidney disease, autoimmune disease, rheumatoid arthritis, and transplant rejection and process for producing said compounds.

THIENO[3,2-b]PYRIDINE-6-CARBONITRILES AND THIENO[2,3-b]PYRIDINE-5-CARBONITRILES AS PROTEIN KINASE INHIBITORS

-

Page 81, (2010/02/07)

This invention provides compounds of Formula (1 a) - (1f) wherein:X, R1, and R2 are defined hereinbefore in the specification, which are useful in the treatment of cancer, stroke, osteoporosis, polycystic kidney disease, autoimmune disease, rheumatoid arthritis, and transplant rejection and process for producing said compounds.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 700844-18-4