70253-78-0

Basic information

• Product Name: 2,2,2-TRIFLUOROETHYL LAURATE
• Synonyms: 2,2,2-TRIFLUOROETHYL LAURATE
• CAS NO: 70253-78-0
• Molecular Formula: C₁₄H₂₅F₃O₂
• Molecular Weight: 282.34
• Mol File: 70253-78-0.mol

Chemical Properties

• Flash Point: 109 °C
• Appearance: /
• Density: 0.999 g/mL at 20 °C(lit.)
• Refractive Index: n20/D 1.403
• CAS DataBase Reference: 2,2,2-TRIFLUOROETHYL LAURATE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2,2-TRIFLUOROETHYL LAURATE(70253-78-0)
• EPA Substance Registry System: 2,2,2-TRIFLUOROETHYL LAURATE(70253-78-0)

Safety Data

• Safety Statements: 24/25
• WGK Germany: 3
• F: 10-21
• Hazardous Substances Data: 70253-78-0(Hazardous Substances Data)

Usage

Uses

Used in Cosmetics and Personal Care Products Industry:
2,2,2-Trifluoroethyl laurate is used as a surfactant or emulsifier for its ability to stabilize mixtures of oil and water, which is crucial in the formulation of creams, lotions, and other personal care products to ensure a smooth texture and even distribution of ingredients.
Used in Pharmaceutical Industry:
In the pharmaceutical sector, 2,2,2-Trifluoroethyl laurate serves as a surfactant or emulsifier in the production of medications, facilitating the mixing of different components and improving the stability and effectiveness of drug formulations.
Used in Polymer and Plastics Industry:
2,2,2-Trifluoroethyl laurate is utilized as a processing aid in the manufacturing of polymers and plastics, enhancing the efficiency of the production process and the quality of the final products by improving the flow and mixing characteristics of the materials.
Used in Agricultural Sector:
2,2,2-Trifluoroethyl laurate has potential applications in agriculture as an ingredient in pesticide or herbicide formulations, leveraging its surfactant properties to improve the delivery and effectiveness of these agrochemicals.
However, due to the chemical properties of 2,2,2-Trifluoroethyl laurate and potential risks to human health and the environment, it is imperative to follow proper handling and disposal procedures when working with this compound.

Upstream product

• 143-07-7 lauric acid 
• 100422-07-9 2,2,2-trifluoroethyl(phenyl)iodonium trifluoromethanesulfonate 
• 112-85-6 n-docosanoic acid 
• 371-67-5 2,2,2-trifluorodiazoethane 

Downstream Products

• 6937-42-4 Dodecanoic acid (R)-sec-butyl ester 
• 6937-42-4 Dodecanoic acid (S)-sec-butyl ester 
• 112-53-8 1-dodecyl alcohol 
• 1204401-74-0 1-O-dodecanoyl-2-O-(6-O-tosyl-β-D-glucopyranosyl)-sn-glycerol 
• 16255-46-2 (2R,3R)-2-[(dichloroacetyl)amino]-3-hydroxy-3-(4-nitrophenyl)propyl laurate 
• 26184-62-3 (S)-2-pentanol 
• 107-87-9 2-Pentanone 
• 55194-05-3 Dodecanoic acid (R)-1-methyl-pentyl ester 
• 160296-83-3 (1S)-1-Methylbutyl dodecanoate 
• 140390-73-4 (1R)-1-Methylbutyl dodecanoate 

Relevant articles and documents

Method for preparing fatty acid trifluoro-ethyl ester without catalysts or condensation agents

The invention discloses a method for preparing fatty acid trifluoro-ethyl ester without catalysts or condensation agents. The method includes steps of mixing fatty acid and alkali with each other to obtain mixtures; adding trifluoro-ethyl aryl trivalence iodine reagents into the mixtures; carrying out stirring reaction at the temperatures ranging from -20 DEC C to 100 DEG C for 1-72 h to obtain reaction products. A molar ratio of the fatty acid to the trifluoro-ethyl aryl trivalence iodine reagents is 1:(0.2-5); a molar ratio of the fatty acid to the alkali is 1:(0.2-5). The method has the advantages that the catalysts and the condensation agents can be omitted, and even organic solvents can be omitted; the trifluoro-ethylation reagents PhICH2CF3[X] can be conveniently synthesized from CF3H2I; raw materials for the fatty acid trifluoro-ethyl ester are easily available, reaction conditions are mild, functional groups are good in compatibility, substrates are wide in application range, the method is easy to implement, and the target products nearly can be obtained under the condition of quantitative yields.

Acid-Catalyzed Reaction of 2,2,2-Trifluorodiazoethane for Analysis of Functional Groups by 19F Nuclear Magnetic Resonance Spectrometry

The acid-catalyzed reactions of trifluorodiazoethane with alcohols, phenols, thiols, and carboxylic acids are reported.The yield data for these trifluoroethyl derivatives suggest a simple, and in many cases, quantitative method for introduction of a fluorine tagging group.The 19F chemical shifts indicate that most functional groups (e.g., phenols, alcohols, etc.) have fairly well resolved chemical shifts regions.In addition, paramagnetic shift reagents have been utilized to selectively differentiate carboxylic acids from other active hydrogen functional groups.