Synthesis of 6α-functionalized estriol haptens and protein conjugates thereof
Disclosed are 6α-derivatized estriol compounds which, when conjugated to a protein, are useful in the in vivo preparation of antibodies specific to estriol. When labeled with a detectable label, the estriol derivatives are useful as haptens in a competitive immunoassay for estriol which demonstrate superior sensitivity with respect to estriol specific antibodies.
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(2008/06/13)
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