748068-32-8

Basic information

• Product Name: Tyrosine, O-ethyl- (9CI)
• Synonyms: Tyrosine, O-ethyl- (9CI);O-Ethyl-DL-tyrosine
• CAS NO: 748068-32-8
• Molecular Formula: C11H15NO3
• Molecular Weight: 209.2417
• Product Categories: ETHOXY
• Mol File: 748068-32-8.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Tyrosine, O-ethyl- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Tyrosine, O-ethyl- (9CI)(748068-32-8)
• EPA Substance Registry System: Tyrosine, O-ethyl- (9CI)(748068-32-8)

Safety Data

• Hazardous Substances Data: 748068-32-8(Hazardous Substances Data)

Upstream product

• 64-67-5 diethyl sulfate 
• 537-55-3 N-acetyl-L-tyrosine 
• 76757-91-0 N-tert-butoxycarbonyl-O-ethyl-L-tyrosine 
• 60-18-4 L-tyrosine 
• 3417-91-2 L-tyrosine methyl ester HCl 
• 3799-87-9 methyl (2,2,2-trifluoroacetyl)-L-tyrosinate 
• 76757-92-1 (R)-2-((tert-butoxycarbonyl)amino)-3-(4-ethoxyphenyl)propanoic acid 

Downstream Products

• 82057-60-1 (S)-3-(4-Ethoxy-phenyl)-2-(2-nitro-phenylsulfanylamino)-propionic acid 
• 85676-28-4 Boc-Tyr(Et)-Arg-OMe_.CH₃COOH 
• 77730-81-5 <2-O-ethyltyrosine>deamino-6-carba-oxytocin 
• 82057-54-3 o-nitrobenzenesulfenyl-O-ethyltyrosyl-isoleucyl-glutaminyl-asparaginyl-S-(β-carboxyethyl)homocysteinyl-prolyl-leucyl-glycine amide 

Relevant articles and documents

Preparation method of L-tyrosine derivative

The invention discloses a preparation method of an L-tyrosine derivative. The L-tyrosine derivative is O-alkyl-N-[fluorenylmethoxycarbonyl]-L-tyrosine, L-tyrosine is used as a starting material, the O-alkyl-N-[fluorenylmethoxycarbonyl]-L-tyrosine is prepared through esterification, amidation, etherification/hydrolysis and amidation in sequence, the total yield of the target product can reach 61.5%, and the ee value can reach 99% or above. The preparation method disclosed by the invention has the advantages of cheap and easily available raw materials, lower cost and the like, for example, separation of triphenylphosphine oxide is avoided through etherification reaction. The method has the advantages of simple process, short route, mild reaction conditions and the like, for example, etherification and hydrolysis adopt a one-pot method; and the whole technological process generates few three wastes, the product yield and purity are high, and the method is suitable for industrial production.

BENZYLAMINE DERIVATIVES AS INHIBITORS OF PLASMA KALLIKREIN

The present invention provides compounds of formula (I): compositions comprising such compounds; the use of such compounds in therapy (for example in the treatment or prevention of a disease or condition in which plasma kallikrein activity is implicated); and methods of treating patients with such compounds; wherein R1 to R9 are as defined herein.

Process to prepare (2S)-2-(dipropylamino)-6-ethoxy-2,3-dihydro-1H-indene-5-carboxamide

The present invention is a process, including intermediates, to produce (2S)-2-dipropylamino)-6-ethoxy-2,3-dihydro-1H-indene-5-carboxamide which is a useful pharmaceutical agent.

Substituted quinoxaline-2-ones as glutamate receptor antagonists

A novel series of substituted quinoxaline 2-ones useful as neuroprotective agents are taught. Novel intermediates, processes of preparation, and pharmaceutical compositions containing the compounds are also taught. The compounds are glutamate receptor antagonists and are useful in the treatment of stroke, cerebral ischemia, or cerebral infarction resulting from thromboembolic or hemorrhagic stroke, cerebral vasospasms, hypoglycemia, cardiac arrest, status epilepticus, perinatal asphyxia, anoxia, seizure disorders, pain, Alzheimer's, Parkinson's, and Huntington's Diseases.

Studies on analgesic oligopeptides. II. Structure-activity relationship among thirty analogs of a cyclic dipeptide, cyclo(-Tyr-Arg-)

Thirty diketopiperazines were synthesized as analogs of cyclo(-Tyr-Arg-). The analgesic activities of these analogs were evaluated after intracerebral administration in mice. In the cyclo(-X-Arg-) series of analogs, cyclo[-Tyr(Et)-Arg-] showed the most po