- USE OF SUBSTITUTED 2 PHENYLBENZIMIDAZOLES AS MEDICAMENTS
-
The present invention relates to the use of a substituted 2-phenylbenzimidazole of formula I wherein R1, R2, R3, R 4, R5 and m have the meanings given in the claims, for the preparation of a medicament for the treatment or prevention of diseases involving glucagon receptors, as well as new compounds of formula I wherein R1 is a group of formula
- -
-
-
- REACTIONS OF OXIDIZED THIOUREAS WITH AMINE NUCLEOPHILES
-
A route for the convenient, cost effective synthesis of di- and tri-substituted guanidines from thioureas has been developed.The key transformation involves activation of the sulfur through S-oxidation followed by displacement of the activated sulfur by a
- Maryanoff, Cynthia A.,Stanzione, Robin C.,Plampin, James N.
-
p. 221 - 232
(2007/10/02)
-