7597-22-0

Basic information

• Product Name: 2-CHLORO-4,6-DIMORPHOLIN-4-YL-1,3,5-TRIAZINE
• Synonyms: 2-CHLORO-4,6-DIMORPHOLIN-4-YL-1,3,5-TRIAZINE;2-CHLORO-4,6-DIMORPHOLINO-1,3,5-TRIAZINE;4,4'-(6-CHLORO-1,3,5-TRIAZINE-2,4-DIYL)DIMORPHOLINE;4-(4-chloro-6-morpholin-4-yl-1,3,5-triazin-2-yl)morpholine;2-Chloro-4,6-di-4-morpholinyl-1,3,5-triazine;EOS-60916
• CAS NO: 7597-22-0
• Molecular Formula: C₁₁H₁₆ClN₅O₂
• Molecular Weight: 285.73004
• Product Categories: Intermediate of BIBF-1120 and PKI587
• Mol File: 7597-22-0.mol

Chemical Properties

• Boiling Point: 508.3 °C at 760 mmHg
• Flash Point: 261.2 °C
• Appearance: /
• Density: 1.375 g/cm³
• Vapor Pressure: 1.88E-10mmHg at 25°C
• Refractive Index: 1.579
• Storage Temp.: Sealed in dry,Store in freezer, under -20°C
• CAS DataBase Reference: 2-CHLORO-4,6-DIMORPHOLIN-4-YL-1,3,5-TRIAZINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLORO-4,6-DIMORPHOLIN-4-YL-1,3,5-TRIAZINE(7597-22-0)
• EPA Substance Registry System: 2-CHLORO-4,6-DIMORPHOLIN-4-YL-1,3,5-TRIAZINE(7597-22-0)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 7597-22-0(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
2-Chloro-4,6-dimorpholin-4-yl-1,3,5-triazine is utilized as a chemical intermediate in the synthesis of various organic compounds. Its unique structure, which includes the triazine ring and morpholine substituents, offers potential for the creation of new molecules with diverse applications.
Due to the limited information available on the compound's properties and applications, further research is necessary to fully understand its potential uses in different industries. This may include exploring its reactivity, stability, and compatibility with other chemicals, as well as assessing any potential hazards associated with its use.

InChI:InChI=1/C11H16ClN5O2/c12-9-13-10(16-1-5-18-6-2-16)15-11(14-9)17-3-7-19-8-4-17/h1-8H2

Upstream product

• 110-91-8 morpholine 
• 108-77-0 1,3,5-trichloro-2,4,6-triazine 

Downstream Products

• 16303-23-4 2,4,6-tris(1-morpholino)-1,3,5-s-triazine 
• 1225037-39-7 bimiralisib 
• 1197159-91-3 4-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)aniline 

Relevant articles and documents

Discovery of ortho-carborane-conjugated triazines as selective topoisomerase I/II inhibitors

The cell growth inhibition profile of 2,4-(2-methyl-ortho-carboranyl)-4- (dimethylamino)-1,3,5-triazine (TAZ-6) was found to be similar to that of ICRF-193, a topoisomerase II inhibitor, as revealed by COMPARE analysis (correlation coefficient (r)≤0.724). Various mono-and di-ortho-carborane- substituted 1,3,5-triazines were synthesized based on the structure of TAZ-6 and tested for their ability to inhibit cell growth and the activities of topoisomerases I and II. Among the compounds synthesized, 3c, 4c, and 4f completely inhibited topoisomerase I activity without affecting topoisomerase II activity, whereas 3a and 3d completely inhibited topoisomerase II activity without affecting topoisomerase I activity, at 100μM.