76006-10-5

Basic information

• Product Name: 7-METHOXY-1H-PYRAZOLO[3,4-C]PYRIDINE
• Synonyms: 7-METHOXY-1H-PYRAZOLO[3,4-C]PYRIDINE;1H-Pyrazolo[3,4-c]pyridine, 7-Methoxy-;7-Methoxy-1H-pyrazolo[3
• CAS NO: 76006-10-5
• Molecular Formula: C₇H₇N₃O
• Molecular Weight: 149.152
• Mol File: 76006-10-5.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 7-METHOXY-1H-PYRAZOLO[3,4-C]PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 7-METHOXY-1H-PYRAZOLO[3,4-C]PYRIDINE(76006-10-5)
• EPA Substance Registry System: 7-METHOXY-1H-PYRAZOLO[3,4-C]PYRIDINE(76006-10-5)

Safety Data

• Hazardous Substances Data: 76006-10-5(Hazardous Substances Data)

Usage

Uses

Used in Chemical Research and Development:
7-Methoxy-1H-pyrazolo[3,4-c]pyridine is used as a research compound for its versatile chemical properties, allowing it to be involved in a wide range of chemical reactions. Its unique structure, featuring a methoxy group and a pyrazoline ring, makes it a valuable component in the synthesis of various compounds, contributing to the advancement of scientific knowledge and the development of new materials and products.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 7-Methoxy-1H-pyrazolo[3,4-c]pyridine is used as a building block for the synthesis of potential drug candidates. Its chemical structure and reactivity make it a promising starting point for the development of new therapeutic agents, with the potential to be optimized for specific medical applications.
Used in Material Science:
7-Methoxy-1H-pyrazolo[3,4-c]pyridine is utilized as a component in the development of novel materials, such as polymers and composites, due to its unique chemical properties. Its incorporation into these materials can lead to improved properties, such as enhanced stability, reactivity, or specific interactions with other molecules, which can be beneficial in various applications, including electronics, coatings, and adhesives.

Upstream product

• 76005-98-6 3-acetamido-2-methoxy-4-methylpyridine 
• 76005-99-7 2-methoxy-3-amino-4-methylpyridine 
• 133627-45-9 3-Amino-2-chloro-4-methylpyridine 

Downstream Products

• 76006-25-2 7-anilino-1H-pyrazolo<3,4-c>pyridine 
• 76006-11-6 7-chloro-1H-pyrazolo<3,4-c>pyridine 
• 76006-09-2 1H-pyrazolo<3,4-c>pyridin-7(6H)-one 

Relevant articles and documents

A pyrazolopyridine compound and method for preparing the same

The invention relates to a pyrazolopyridine compound and a preparation method thereof. The compound is 3-bromo-1H-pyrazolo[3,4-c]pyridine-7(6H)-one, and the preparation method comprises the following steps: (1) by taking the compound 1 2-chloro-3-amino-4methylpyridine as a starting raw material, etherifying 2-chloro-3-amino-4methylpyridine through sodium methoxide under the catalysis of copper iodide; (2) closing pyrazole ring through isoamyl nitrite; (3) feeding pyrazol-3 through NBS (N-Bromosuccinimide); (4) removing methoxyl to obtain phenyl (mixture difficult to separate) through pyridine hydrochloride; (5) performing acetyl protection to the obtained mixture so as to separate and purify; and (6) deacetylating through using potassium carbonate as a base to obtain a final product; and according to the preparation method, the mixture difficult to purify in the reaction process is conveniently separated and purified by adopting a method of performing protection and then removing protection, and the purification difficulty caused by instability of an intermediate product can be solved.

A pyrazole compound pyridine and its preparation method

The invention relates to a pyrazolo pyridine compound and a preparation method thereof. The pyrazolo pyridine compound is 3-bromine-7-hydroxy-pyrazolo pyridine. The preparation method comprises the following steps: (1) carrying out substitution reaction on 12-chlorine-4-methyl-3-aminopyridine as an initial raw material to form a compound 2; (2) carrying out ring closure on the compound 2 to form a compound 3, namely pyrazolo pyridine; (3) bromizing the compound 3 by adopting N-bromosuccinimide to obtain a compound 4; (4) forming the methoxyl of the compound 4 into a phenolic hydroxyl group by utilizing hydrochloric pyridine to obtain a compound 5a; (5) carrying out acetyl protection on the compound 5a to obtain a compound 6a; and (6) eliminating the acetyl protection on the compound 6 to obtain a final product, namely a compound 7. The obtained final product has a wide application prospect on the aspects of preventing and curing cancer.

Pyrazolopyridines. Part 5. Preparation and Reactions of Pyrazolopyridines

A series of pyrazolopyridines has been prepared by nitrosation of 3-acetamido-4-methylpyridines and subsequent rearrangement and cyclisation of the N-acetyl-N-nitroso-compounds produced.The reactions of the pyrazolopyridines have been investigated. 1- and 2-Acetyl and 1- and 2-benzyl compounds were obtained and their structures elucidated spectroscopically.The ring system readily undergoes electrophilic substitution in the 3-position. 7-Chloropyrazolopyridine has been shown to be more susceptible to nucleophilic substitution than the isomeric 5-chloro-compound.