- N-SUBSTITUTED PIPERIDINE AND PIPERAZINE DERIVATIVES
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This invention relates to compounds of the formula 1 wherein R1, R2, R7, R8, R9, U, V, Z, A, W, X, M, E, L, T and D are defined as in the specification, pharmaceutical compositions containing them and their use in the treatment of central nervous system and other disorders.
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Page/Page column 122
(2010/02/12)
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- 5-heteroyl indole derivatives
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Compounds of the formula STR1 which are useful in treating migraine and other disorders, and intermediates used in the preparation of said compounds.
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- Indole-Phenol Bioisosterism. Synthesis and Antihypertensive Activity of a Pyrrolo Analogue of Labetalol
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The synthesis of 5-ethyl>-1H-indole-7-carboxamide, 5, a pyrrolo analogue of labetalol, is described.Compound 5 was found to reduce blood pressure in spontaneously hypertensive rats with an ED50 of 5 mg/kg po, wit
- Asselin, Andre A.,Humber, Leslie G.,Crosilla, Danilo,Oshiro, George,Wojdan, Alexandra,et al.
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p. 1009 - 1015
(2007/10/02)
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