76179-43-6

Basic information

• Product Name: 1,2-DIAMINO-4,5-DIIODOBENZENE
• Synonyms: 4,5-DIIODO-BENZENE-1,2-DIAMINE;1,2-DIAMINO-4,5-DIIODOBENZENE
• CAS NO: 76179-43-6
• Molecular Formula: C₆H₆I₂N₂
• Molecular Weight: 359.93
• Mol File: 76179-43-6.mol

Chemical Properties

• Melting Point: 135-136 °C(Solv: ethanol (64-17-5); water (7732-18-5))
• Boiling Point: 397.2±42.0 °C(Predicted)
• Appearance: /
• Density: 2.605±0.06 g/cm3(Predicted)
• PKA: 2.70±0.10(Predicted)
• CAS DataBase Reference: 1,2-DIAMINO-4,5-DIIODOBENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-DIAMINO-4,5-DIIODOBENZENE(76179-43-6)
• EPA Substance Registry System: 1,2-DIAMINO-4,5-DIIODOBENZENE(76179-43-6)

Safety Data

• Hazardous Substances Data: 76179-43-6(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
1,2-Diamino-4,5-diiodobenzene is used as a building block for the preparation of various pharmaceuticals and dyes. Its reactivity allows it to be a key component in the synthesis of complex organic molecules.
Used in Pharmaceutical Industry:
1,2-Diamino-4,5-diiodobenzene is used as a precursor in the development of new drugs. Its unique structure and reactivity make it a valuable compound for creating novel pharmaceutical agents.
Used in Dye Industry:
1,2-Diamino-4,5-diiodobenzene is used as a starting material for the production of dyes. Its chemical properties contribute to the creation of dyes with specific characteristics and applications.
Safety Precautions:
Due to its reactivity and potential health hazards, proper precautions must be taken when handling and working with 1,2-diamino-4,5-diiodobenzene. It is important to use appropriate protective equipment, such as gloves and a lab coat, and to work in a well-ventilated area.

Upstream product

• 29270-47-1 1,2-diiodo-4,5-dinitrobenzene 
• 29270-48-2 2-nitro-4,5-di-iodoaniline 
• 528-29-0 1,2-Dinitrobenzene 

Downstream Products

• 887928-83-8 2-(4-iodo-phenyl)-1H-benzoimidazole-5,6-dicarbonitrile 
• 887928-86-1 5,6-dicyano-2-phenyl-1-propylbenzimidazole 
• 887928-84-9 5,6-dicyano-2-(4-(triisopropylsilylethynyl)phenyl)benzimidazole 
• 887928-88-3 5,6-dicyano-2-(4-(triisopropylsilylethynyl)phenyl)-1-propylbenzimidazole 
• 887928-96-3 2-(4-(2-(triisopropylsilyl)ethynyl)phenyl)-1-propylimidazo[4,5-f]isoindole-1,3-diimine 
• 14320-04-8 zinc(II) phthalocyanine 
• 825613-16-9 2-phenylbenzimidazole-5,6-dicarbonitrile 
• 129365-93-1 4,5-diaminophthalonitrile 

Relevant articles and documents

Synthesis of novel halogenated heterocycles based on o‐phenylenediamine and their interactions with the catalytic subunit of protein kinase ck2

Protein kinase CK2 is a highly pleiotropic protein kinase capable of phosphorylating hundreds of protein substrates. It is involved in numerous cellular functions, including cell viability, apoptosis, cell proliferation and survival, angiogenesis, or ER‐stress response. As CK2 activity is found perturbed in many pathological states, including cancers, it becomes an attractive target for the pharma. A large number of low‐mass ATP‐competitive inhibitors have already been developed, the majority of them halogenated. We tested the binding of six series of halogenated heterocyclic ligands derived from the commercially available 4,5‐dihalo‐benzene‐1,2‐diamines. These ligand series were selected to enable the separation of the scaffold effect from the hydrophobic interactions attributed directly to the presence of halogen atoms. In silico molecular docking was initially applied to test the capability of each ligand for binding at the ATP‐binding site of CK2. HPLC‐derived ligand hydrophobicity data are compared with the binding affinity assessed by low‐volume differential scanning fluorimetry (nanoDSF). We identified three promising ligand scaffolds, two of which have not yet been described as CK2 inhibitors but may lead to potent CK2 kinase inhibitors. The inhibitory activity against CK2α and toxicity against four reference cell lines have been determined for eight compounds identified as the most promising in nanoDSF assay.

Substituted benzazoloporphyrazines for polymerization and surface attachment and articles formed therefrom

The present invention provides an article of manufacture formed from a substrate and a benzazoloporphyrazine bound to the substrate. The article may take a variety of different forms and may be for example an electrochromic display, a molecular capacitor, a battery, a solar cell, or a molecular memory device. Methods of making such articles, along with compounds, methods and intermediates useful for making such benzazoloporphyrazines, are also described.

Synthesis, properties and in vitro photodynamic activity of water-soluble azaphthalocyanines and azanaphthalocyanines

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Synthesis of a new trans-A2B2 phthalocyanine motif as a building block for rodlike phthalocyanine polymers

Polyphthalocyanines have potential application in the development of electronic materials. One-dimensional polyphthalocyanines are accessible through monomers having a trans-A2B2 structure, but the preparation of a truly linear polyphthalocyanine is challenging because of limitations imposed by the geometry of phthalocyanines and the methodology for their synthesis. Benzimidazoporphyrazines are a known class of extra-annulated phthalocyanines. A trans-A2B2 benzimidazoporphyrazine is geometrically suitable for the preparation of rodlike polymers. A new synthesis of benzimidazoporphyrazines is presented as a stepping stone to the synthesis of trans-A2B2 benzimidazoporphyrazines.

CHARGE-TRANSPORT MATERIALS, METHODS OF FABRICATION THEREOF, AND METHODS OF USE THEREOF

Briefly described, embodiments of this disclosure include charge-transport materials, methods of forming charge-transport materials, and methods of using the charge-transport materials.

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Salts of 6,7-dihalo-3,4-dihydro-3-oxo-2-quinoxaline carboxylic acids and hindered amines, useful in combating influenza A and B.

Treatment of influenza with 2-estersubstituted-3,4-dihydro-3-oxoquinoxalines

3,4-Dihydro-3-oxoquinoxalines carrying a carboxylic acid or ester function in the 2 position, used as antiviral agents, particularly against influenza virus, both A and B strains.