Welcome to LookChem.com Sign In|Join Free

CAS

  • or
4-(Benzyloxy)-2-bromophenol is an organic compound characterized by the presence of a benzyloxy group attached to the 4-position and a bromine atom at the 2-position of a phenol molecule. This unique structure endows it with specific chemical properties that make it a valuable intermediate in the synthesis of various pharmaceutical compounds.

79352-66-2 Suppliers

Post Buying Request

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier
  • 79352-66-2 Structure
  • Basic information

    1. Product Name: 4-(benzyloxy)-2-bromophenol
    2. Synonyms: 4-(benzyloxy)-2-bromophenol
    3. CAS NO:79352-66-2
    4. Molecular Formula: C13H11BrO2
    5. Molecular Weight: 279.12924
    6. EINECS: -0
    7. Product Categories: N/A
    8. Mol File: 79352-66-2.mol
  • Chemical Properties

    1. Melting Point: 72-73 °C(Solv: ligroine (8032-32-4))
    2. Boiling Point: 370.0±27.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.478±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: Sealed in dry,Room Temperature
    8. Solubility: N/A
    9. PKA: 8.79±0.20(Predicted)
    10. CAS DataBase Reference: 4-(benzyloxy)-2-bromophenol(CAS DataBase Reference)
    11. NIST Chemistry Reference: 4-(benzyloxy)-2-bromophenol(79352-66-2)
    12. EPA Substance Registry System: 4-(benzyloxy)-2-bromophenol(79352-66-2)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 79352-66-2(Hazardous Substances Data)

79352-66-2 Usage

Uses

Used in Pharmaceutical Synthesis:
4-(Benzyloxy)-2-bromophenol is used as an intermediate in the synthesis of (S)-4-Hydroxy Penbutolol Hydrochloride (H948945), a hydroxylated metabolite of Penbutolol (P220500). This intermediate plays a crucial role in the production of pharmaceuticals, contributing to the development of medications with potential therapeutic benefits.

Check Digit Verification of cas no

The CAS Registry Mumber 79352-66-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,9,3,5 and 2 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 79352-66:
(7*7)+(6*9)+(5*3)+(4*5)+(3*2)+(2*6)+(1*6)=162
162 % 10 = 2
So 79352-66-2 is a valid CAS Registry Number.

79352-66-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-(benzyloxy)-2-bromophenol

1.2 Other means of identification

Product number -
Other names 4-benzyloxy-2-bromo-phenol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:79352-66-2 SDS

79352-66-2Relevant articles and documents

Synthesis of novel 2H-spiro[1-benzofuran-3,4′-piperidin]ol scaffolds

Leflemme, Nicolas,Stoit, Axel R.,Borghese, Alfio

experimental part, p. 2432 - 2435 (2012/06/01)

With the aim to enrich our 'privileged structure'-based library, novel 2H-spiro[1-benzofuran-3,4′-piperidin]ol scaffolds were prepared. The method involved a key intramolecular Heck cyclization which was successfully applied for three series of compounds.

OXAZOLE AND THIAZOLE PPAR MODULATORS

-

Page/Page column 25, (2010/11/27)

The invention provides compounds (I) pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of the Peroxisome Proliferator-Activated Receptor (PPAR) families, particularly the activity of PPARδ.

COMPOUNDS AND COMPOSITIONS AS PPAR MODULATORS

-

Page/Page column 57, (2008/06/13)

The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of the Peroxisome Proliferator-Activated Receptor (PPAR) families.

COMPOUNDS AND COMPOSITIONS AS PPAR MODULATORS

-

Page/Page column 44-45, (2010/11/27)

The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of the Peroxisome Proliferator-Activated Receptor (PPAR) families.

Novel imidazotriazinones and the use thereof

-

, (2008/06/13)

Novel imidazotrizinones of general formula (I), a method for the production and the pharmaceutical use thereof are disclosed.

COMPOUNDS WITH MIXED PDE-INHIBITORY AND β-ADRENERGIC ANTAGONIST OR PARTIAL AGONIST ACTIVITY FOR TREATMENT OF HEART FAILURE

-

Page 70, (2010/02/07)

This invention provides compounds that possess inhibitory activity against β--adrenergic receptors and phosphodiesterase PDE, including phosphodiesterase 3 (PDE3 ). This invention further provides pharmaceutical compositions comprising such -compounds; methods of using such compounds for treating cardiovascular disease, stroke, epilepsy, ophthalmic disorder or migraine; and methods of preparing pharmaceutical compositions and compounds that possess inhibitory activity against ?-adrenergic receptors and PDE.

A modular approach to structurally diverse bidentate chelate ligands for transition metal catalysis

Kranich, Remo,Eis, Knut,Geis, Oliver,Muehle, Stefan,Bats, Jan W.,Schmalz, Hans-Guenther

, p. 2874 - 2894 (2007/10/03)

A modular approach to a new class of structurally diverse bidentate P/N, P/P, P/S, and P/Se chelate ligands has been developed. Starting from hydroquinone, various ligands were synthesized in a divergent manner via orthogonally bis-protected bromohydroqui

The Synthesis of 5-Substituted 2,3-Dihydrobenzofurans

Alabaster, Ramon J.,Cottrell, Ian F.,Marley, Hugh,Wright, Stanley H. B.

, p. 950 - 952 (2007/10/02)

The preparation of 2,3-dihydrobenzofurans 6 from 2-(2-bromophenoxy)ethyl chlorides 3 by reaction with magnesium in a development of the Parham cyclialkylation reaction is described.A high yielding procedure using phase-transfer catalysis has also been developed for the preparation of the intermediate chloroethyl ethers 3 from bromophenols 2.The 5-hydroxy derivative 15 may be obtained from 2,3-dihydrobenzofuran (6a) by reaction with electrophilic reagents followed by oxidation.

A New Route to Anthraquinones

Dodsworth, David J.,Calcagno, Maria-Pia,Ehrmann, E. Ursula,Devadas, Bhatt,Sammes, Peter G.

, p. 2120 - 2124 (2007/10/02)

The lithium salts derived from position 3 of phthalides react with arynes to form adducts, which, upon aerial oxidation, produce anthraquinones in moderate to good yields.Substituted phthalides and arynes also participate in this general reaction.The addition to unsymmetrically substituted arynes shows regioselectivity, whilst the availability of a new general route to phthalides extends the scope of this reaction.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 79352-66-2