794549-90-9

Basic information

• Product Name: 3-(4-chlorobenzyl)-6-(4-fluorophenyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
• Synonyms: 3-(4-chlorobenzyl)-6-(4-fluorophenyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
• CAS NO: 794549-90-9
• Molecular Formula: C16H10ClFN4S
• Molecular Weight: 344.7938032
• Mol File: 794549-90-9.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-(4-chlorobenzyl)-6-(4-fluorophenyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-chlorobenzyl)-6-(4-fluorophenyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole(794549-90-9)
• EPA Substance Registry System: 3-(4-chlorobenzyl)-6-(4-fluorophenyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole(794549-90-9)

Safety Data

• Hazardous Substances Data: 794549-90-9(Hazardous Substances Data)

Upstream product

• 456-22-4 4-Fluorobenzoic acid 
• 93073-15-5 4-Amino-5-(4-chloro-benzyl)-4H-[1,2,4]triazole-3-thiol 
• 66464-84-4 C₉H₈ClN₂OS₂^(1-)*K⁽¹⁺⁾ 
• 57676-51-4 2-(4-chlorophenyl)acetic hydrazide 
• 52449-43-1 (4-chloro-phenyl)-acetic acid methyl ester 
• 1878-66-6 4-chlorophenylacetic Acid 

Relevant articles and documents

Synthesis, Antimicrobial, and Antioxidant Screening of Aryl Acetic Acid Incorporated 1,2,4-Triazolo-1,3,4-Thiadiazole Derivatives

Some novel [1,2,4]triazolo[3,4-b][1,3,4]thiadiazole derivatives were synthesized from aryl acetic acids. All the synthesized derivatives were selected for the screening of antibacterial potential against Gram-positive bacteria [Staphylococcus aureus (MTCC 3160) and Micrococcus luteus (MTCC 1538)] and Gram-negative bacteria [Escherichia coli (MTCC 1652) and Pseudomonas aeruginosa (MTCC 424)] and antifungal potential against Aspergillus niger (MTCC 8652) and Candida albicans (MTCC 227), and free radical scavenging activity through 2,2-diphenyl-2-picrylhydrazyl hydrate method. The compounds TH-4, TH-13, and TH-19 were found to be more potent antimicrobial agents compared to standard drugs. The compounds TH-3, TH-9, and TH-18 also showed significant antimicrobial activity. The compound TH-13 showed antioxidant activity with IC50 value better than the standard compound. The structures of all the synthesized compounds were confirmed by Fourier transform infrared, 1H-NMR, liquid chromatography–mass spectrometry, and CHN analyzer.