800402-12-4

Basic information

• Product Name: 2-Chloro-5-iodo-4-pyridinamine
• Synonyms: 2-Chloro-5-iodo-4-pyridinamine;4-Amino-2-chloro-5-iodopyridine;4-Amino-5-iodo-2-chloropyridine;2-Chloro-5-iodo-pyridin-4-ylamine
• CAS NO: 800402-12-4
• Molecular Formula: C₅H₄ClIN₂
• Molecular Weight: 254.454
• Mol File: 800402-12-4.mol

Chemical Properties

• Melting Point: 126-127°
• Boiling Point: 367.751°C at 760 mmHg
• Flash Point: 176.21°C
• Appearance: /
• Density: 2.139g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.708
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 2.96±0.42(Predicted)
• Sensitive: Light Sensitive
• CAS DataBase Reference: 2-Chloro-5-iodo-4-pyridinamine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Chloro-5-iodo-4-pyridinamine(800402-12-4)
• EPA Substance Registry System: 2-Chloro-5-iodo-4-pyridinamine(800402-12-4)

Safety Data

• Hazard Codes: Xi
• Statements: 22-41
• Safety Statements: 26-39
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 800402-12-4(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Synthesis:
2-Chloro-5-iodo-4-pyridinamine is used as an intermediate in the synthesis of various pharmaceuticals for its ability to be transformed into a range of biologically active compounds. Its presence as a building block facilitates the creation of new drugs with potential therapeutic applications.
Used in Medicinal Research:
In the field of medicinal research, 2-Chloro-5-iodo-4-pyridinamine is utilized as a valuable component for the development of new chemical entities. Its unique structure with halogen substituents allows for the exploration of its potential biological activities and its integration into novel therapeutic agents.
Used in Agrochemical Research:
2-Chloro-5-iodo-4-pyridinamine also finds applications in agrochemical research, where it serves as a key intermediate in the synthesis of compounds with pesticidal or herbicidal properties. Its reactivity and structural features make it suitable for the development of new agrochemicals aimed at enhancing crop protection and yield.
Used in Organic Chemistry:
As a reactive chemical compound, 2-Chloro-5-iodo-4-pyridinamine is employed in organic chemistry for various chemical transformations. Its ability to undergo different reactions under suitable conditions makes it a useful tool for the synthesis of complex organic molecules and the exploration of new reaction pathways.

InChI:InChI=1/C5H4ClIN2/c6-5-1-4(8)3(7)2-9-5/h1-2H,(H2,8,9)

Upstream product

• 14432-12-3 4-Amino-2-chloropyridine 
• 657408-07-6 dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane 
• 1251041-55-0 3-chlorobenzofuran[3,2-c]pyridine 
• 98-80-6 phenylboronic acid 

Downstream Products

• 1137477-86-1 tert-butyl 4-(((2-chloro-5-iodopyridin-4-yl)amino)methyl)piperidine-1-carboxylate 
• 1235873-05-8 2-chloro-5-(4-bromophenylthio)-4-aminopyridine 
• 1223577-54-5 6-chloro-2,3-diphenyl-1H-pyrrolo[3,2-c]pyridine 
• 1300750-94-0 6-chloro-2,3-bis(4-methoxyphenyl)-1H-pyrrolo[3,2-c]-pyridine 
• 1392003-16-5 2-N-benzyl-5-iodopyridine-2,4-diamine 
• 1392003-17-6 4-benzyl-N-{[6-(benzylamino)-1H-pyrrolo[3,2-c]pyridin-2-yl]methyl}piperidine-1-carboxamide 
• 1392002-52-6 2,2,2-trifluoroacetic acid; N-({6-amino-1H-pyrrolo[3,2-c]pyridin-2-yl}methyl)-4-benzylpiperidine-1-carboxamide 
• 1137478-11-5 tert-butyl 4-((2-chloro-5-(4-methoxyphenyl)pyridin-4-ylamino)methyl)-4-fluoropiperidine-1-carboxylate 
• 1137478-12-6 5-(4-((4-fluoropiperidin-4-yl)methylamino)-5-(4-methoxyphenyl)pyridin-2-ylamino)pyrazine-2-carbonitrile 
• 1137478-13-7 tert-butyl 4-((2-(5-cyanopyrazin-2-ylamino)-5-(4-methoxyphenyl)pyridin-4-ylamino)methyl)-4-fluoropiperidine-1-carboxylate 
• 1404095-61-9 2-chloro-5-(3-fluorophenyl)-N-methylpyridin-4-amine 
• 1404095-27-7 C₂₂H₂₄FN₇O 
• 1296200-83-3 N-(3-methoxybenzyl)-6-(1H-pyrazol-4-yl)-1H-pyrrolo[3,2-c]pyridine-2-carboxamide 
• 1296203-15-0 C₁₆H₁₄ClN₃O₂ 

Relevant articles and documents

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