80443-63-6

Basic information

• Product Name: 2-[2-(4-Chlorophenyl)ethyl]-2-(1,1-dimethylethyl)-oxirane
• Synonyms: 2-[2-(4-chlorophenyl)ethyl-(1,1-dimethyl)]oxirane (intermediate of tebuconazole);EPOXIDE-INTERMEDIATE;2-TERT-BUTYL-2-[2-(4-CHLOROPHENYL)ETHYL]OXIRANE [FOR TEBUCONAZOLE];2-[2-(4-CHLOROPHENYL)ETHYL-(1,1-DIMETHYL)]OXIRANE;2-tert-Butyl-2-[2-(4-chlorophenyl)ethyl]oxirane;2-tert-Butyl-2-[2-(4-chlorophenyl)ethyl]oxirane;2-(2-(4-CHLOROPHENYL)ETHYL)-2-(1,1-DIMETHYLETHYL)OXIRANE;2-[2-(4-CHLOROPHENYL) ETHYL]-2-(1,1-DIMETHYL) OXIRANE
• CAS NO: 80443-63-6
• Molecular Formula: C₁₄H₁₉ClO
• Molecular Weight: 238.75
• Product Categories: (intermediate of tebuconazole);Oxiranes;Simple 3-Membered Ring Compounds
• Mol File: 80443-63-6.mol

Chemical Properties

• Boiling Point: 302.1 °C at 760 mmHg
• Flash Point: 138.4 °C
• Appearance: Light yellow to yellow liquid
• Density: 1.06
• Vapor Pressure: 0.00181mmHg at 25°C
• Refractive Index: 1.5150-1.5190
• Storage Temp.: Refrigerator
• Solubility: Chloroform, Methanol (Slightly)
• CAS DataBase Reference: 2-[2-(4-Chlorophenyl)ethyl]-2-(1,1-dimethylethyl)-oxirane(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[2-(4-Chlorophenyl)ethyl]-2-(1,1-dimethylethyl)-oxirane(80443-63-6)
• EPA Substance Registry System: 2-[2-(4-Chlorophenyl)ethyl]-2-(1,1-dimethylethyl)-oxirane(80443-63-6)

Safety Data

• RTECS: RQ2850750
• Hazardous Substances Data: 80443-63-6(Hazardous Substances Data)

Usage

Uses

Used in Agriculture:
2-[2-(4-Chlorophenyl)ethyl]-2-(1,1-dimethylethyl)-oxirane is used as an insect growth regulator for controlling various pests in crops. It functions by inhibiting chitin synthesis, which is essential for the proper growth and development of insects, ultimately disrupting their life cycle.
Used in Rice and Cotton Crops:
In the rice and cotton industries, 2-[2-(4-Chlorophenyl)ethyl]-2-(1,1-dimethylethyl)-oxirane is used as a pest control agent to protect these crops from damage caused by insects. Its application helps maintain crop health and yield, contributing to more efficient and sustainable agricultural practices.

InChI:InChI=1/C14H19ClO/c1-13(2,3)14(10-16-14)9-8-11-4-6-12(15)7-5-11/h4-7H,8-10H2,1-3H3

Upstream product

• 66346-01-8 1-(4-chlorophenyl)-4,4-dimethyl-pentan-3-one 
• 77-78-1 dimethyl sulfate 
• 74-88-4 methyl iodide 
• 3084-53-5 trimethylsulphonium bromide 
• 2181-42-2 trimethylsulphonium iodide 
• 3086-29-1 trimethylsulfonium chloride 

Downstream Products

• 107534-96-3 tebuconazole 
• 353736-62-6 tebuconazole 
• 1350799-79-9 C₁₇H₂₁Cl₂NOS 

Relevant articles and documents

Method for preparing 2-[2-(4-chlorphenyl)ethyl]-2-(1,1-dimethyl ethyl) ethylene oxide

The invention relates to a method for preparing 2-[2-(4-chlorphenyl)ethyl]-2-(1,1-dimethyl ethyl) ethylene oxide. The method comprises the following steps: adding a solvent, a raw material B and alkali into a reactor, and stirring for 0.2-1 hour; dropping 1-(4-chlorphenyl)-4,4-dimethyl-3-pentanone (raw material A) to react, thereby obtaining the 2-[2-(4-chlorphenyl)ethyl]-2-(1,1-dimethyl ethyl) ethylene oxide (formula C). The structural general formula of the raw material B is as shown in the description. In the formula, X is chlorine, bromine or iodine. The raw materials are readily available, the odor is small, the toxicity of reagents and drugs used in the operating process is relatively low, the reaction condition is mild, the time is short, and the odor is smaller than that of commondimethyl sulfide. Meanwhile, when methylbenzene serves as a solvent, the cost is low, the amount of three wastes is small, the content of target products is high, and the method is very suitable for industrial production.

Synthesis method for ethylene oxide derivative

The invention discloses a synthesis method for an ethylene oxide derivative, which is an important intermediate for pesticides and medicines. The synthesis method includes the steps of performing a reaction to alkoxy phenyl sulfide (IV) with a methylation reagent at 70-90 DEG C to synthesize sulfonium salt (III); and then performing a reaction to the sulfonium salt (III) with a carbonyl compound (II) under alkali condition to generate the ethylene oxide derivative (I). In the method, sulfur ylide is synthesized by using the alkoxy phenyl sulfide, which is difficult to volatilize and is low in odor, instead of dimethyl sulfide, which is toxic and malodorous, in a conventional method, so that a problem of malodorous odor generated during production is solved from the source, and environment stress is greatly alleviated. Meanwhile, the alkoxy phenyl sulfide can be recycled, so that industrial cost is reduced and production efficiency is increased. The method is environment-friendly and high-effectively and can be used for synthesizing various ethylene oxide derivatives as pesticide and medicine intermediates.