66346-01-8 Usage
Description
1-(4-Chlorophenyl)-4,4-dimethyl-3-pentanone, commonly known as PDCPD, is a chemical compound with the molecular formula C13H17ClO. It is a colorless liquid characterized by a strong, sweet odor. PDCPD is recognized for its versatile applications in various industrial processes, primarily as a solvent, and also as an intermediate in the synthesis of other organic compounds.
Uses
Used in Chemical Industry:
1-(4-Chlorophenyl)-4,4-dimethyl-3-pentanone is used as a solvent for its ability to dissolve a wide range of substances, which is crucial in the production of adhesives, coatings, and pharmaceuticals. Its solvent properties facilitate the manufacturing process by ensuring proper mixing and adherence of components.
Used in Pharmaceutical Industry:
In the pharmaceutical sector, PDCPD serves as an intermediate in the synthesis of various organic compounds, contributing to the development of new drugs and medicinal formulations. Its role in synthesis is vital for creating complex molecules that address specific medical needs.
Used in Adhesives and Coatings Industry:
PDCPD is utilized as a component in the formulation of adhesives and coatings, enhancing their performance characteristics such as adhesion strength, durability, and resistance to environmental factors. Its presence in these formulations is essential for achieving optimal product quality and performance.
Safety Considerations:
Given its flammable nature, 1-(4-Chlorophenyl)-4,4-dimethyl-3-pentanone requires careful handling to prevent fire hazards. Additionally, due to its potential to cause irritation to the skin, eyes, and respiratory tract, it is imperative to use appropriate protective equipment and ensure proper ventilation during its storage and use. Ingestion or inhalation of PDCPD may have harmful effects, necessitating strict adherence to safety protocols to minimize health risks.
Check Digit Verification of cas no
The CAS Registry Mumber 66346-01-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,6,3,4 and 6 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 66346-01:
(7*6)+(6*6)+(5*3)+(4*4)+(3*6)+(2*0)+(1*1)=128
128 % 10 = 8
So 66346-01-8 is a valid CAS Registry Number.
InChI:InChI=1/C13H17ClO/c1-13(2,3)12(15)9-6-10-4-7-11(14)8-5-10/h4-5,7-8H,6,9H2,1-3H3
66346-01-8Relevant articles and documents
Synthesis method of 1-(4-chlorphenyl)-4,4-dimethyl-3-pentanone
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Paragraph 0043; 0049-0050; 0054; 0057-0059; 0062-0064; 0067, (2020/08/27)
The invention discloses a synthetic method of 1-(4-chlorphenyl)-4,4-dimethyl-3-pentanone. The target compound is prepared through condensation, hydrolysis and decarboxylation, the middle-high pressurehydrogenation step of a traditional process is omitted, and safety is remarkably improved. The method is mild in reaction condition, simple in process and suitable for industrial production.
Design, synthesis and neuraminidase inhibitory activity of N-(5-benzyl-4-(tert-butyl)thiazol-2-yl)benzamides
Wu, Zhilin,Peng, Junmei,Hu, Aixi,Ye, Jiao,Li, Guoxi
, p. 356 - 368 (2016/01/25)
A series of N-(5-benzyl-4-(tert-butyl)thiazol-2-yl)benzamides were synthesized and the structures were characterized by 1H NMR, MS and elemental analyses. The crystal structures of compounds F5 and F16 were determined by single-crystal X-ray diffraction. The neuraminidase inhibitory activities of compounds F1-F32 were evaluated in vitro at the concentration of 40 μg/mL. The results indicated that compounds F8, F26 and F32 exhibited most potent inhibitory activity against NA. Molecular docking was performed by LeDock to further explain the structure-activity relationship of compound F26. The docking modeling showed that compound F26 was in good combination with oseltamivir binding sites of NA and could be a potential NA inhibitor agent.
Process for the hydrogenation of α,β-unsaturated ketones
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, (2008/06/13)
The catalytic hydrogenation of α,β-unsaturated ketones of the formula in which R1 and R2 independently of one another represent straight-chain or branched alkyl, hydroxy-alkyl, alkenyl, cycloalkyl, cycloalkenyl, aralkyl or aryl, where at least one of the radicals R1 and R2 is monosubstituted to trisubstituted by halogen, can be carried out on a Ni-containing catalyst and in the presence of an organic sulphur compound of the formula in which R3 and R4 independently of one another denote straight-chain or branched alkyl, hydroxy-alkyl, carboxyalkyl or phenyl, and furthermore R3 and R4 may together represent --CH=CH--CH=CH--, --(CH2)4 --, --(CH2)5 --, --(CH2)2 --S--(CH2)2 -- or --(CH2)2 --O--(CH2)2 --, R4 may additionally denote hydrogen or CO--C1 -C12 -alkyl and n assumes the value 0 or 1.