81110-69-2Relevant articles and documents
Trifluoromethyl Thianthrenium Triflate: A Readily Available Trifluoromethylating Reagent with Formal CF3+, CF3?, and CF3-Reactivity
Jia, Hao,H?ring, Andreas P.,Berger, Florian,Zhang, Li,Ritter, Tobias
supporting information, p. 7623 - 7628 (2021/05/26)
Here we report the synthesis and application of trifluoromethyl thianthrenium triflate (TT-CF3+OTf-) as a novel trifluoromethylating reagent, which is conveniently accessible in a single step from thianthrene and triflic anhydride. We demonstrate the use of TT-CF3+OTf- in electrophilic, radical, and nucleophilic trifluoromethylation reactions.
"Mixed Inhibitor-Prodrug" as a New Approach toward Systemically Active Inhibitors of Enkephalin-Degrading Enzymes
Fournie-Zaluski, Marie-Claude,Coric, Pascal,Turcaud, Serge,Lucas, Evelyne,Noble, Florence,et al.
, p. 2473 - 2481 (2007/10/02)
In order to evaluate the possible advantages of potentiating the effects of the endogenous enkephalins, to obtain analgesia without the serious drawbacks of morphine, it was essential to design systemically active compounds which inhibit the two metaboliz
AMINOACID DERIVATIVES AND THEIR THERAPEUTIC APPLICATIONS
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, (2008/06/13)
This invention relates to aminoacid derivatives, and compositions containing the same and having enkephalinase-inhibiting, antalgic, antidiarrhea and hypotensive activities, of the formula STR1 whose variables are as set forth herein, for example STR2