819070-53-6 Usage
Uses
Used in Pharmaceutical Industry:
(4-CHLORO-2-CYANOPHENYL)BORONIC ACID is used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the production of 4-arylpiperidines. These 4-arylpiperidines are important structural motifs found in a variety of bioactive molecules, including antidepressants, antipsychotics, and other central nervous system (CNS) active drugs. The incorporation of the chloro-cyanophenyl moiety in these compounds can potentially enhance their pharmacological properties, such as potency, selectivity, and metabolic stability.
Used in Organic Synthesis:
In the field of organic synthesis, (4-CHLORO-2-CYANOPHENYL)BORONIC ACID serves as a valuable building block for the construction of complex organic molecules. Its reactivity allows it to participate in various chemical reactions, such as cross-coupling reactions, which can be used to form carbon-carbon or carbon-heteroatom bonds. This makes it a useful tool for the synthesis of a wide range of organic compounds, including natural products, pharmaceuticals, and functional materials.
Used in Material Science:
(4-CHLORO-2-CYANOPHENYL)BORONIC ACID can also be utilized in the development of new materials with unique properties. For instance, its incorporation into polymers or other macromolecular structures can lead to materials with improved mechanical, thermal, or electronic properties. Additionally, the presence of the boronic acid group may enable the formation of reversible covalent bonds with specific targets, such as sugars or nucleic acids, which could be useful in the design of responsive or adaptive materials.
Check Digit Verification of cas no
The CAS Registry Mumber 819070-53-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,1,9,0,7 and 0 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 819070-53:
(8*8)+(7*1)+(6*9)+(5*0)+(4*7)+(3*0)+(2*5)+(1*3)=166
166 % 10 = 6
So 819070-53-6 is a valid CAS Registry Number.
819070-53-6Relevant articles and documents
An efficient synthesis of a highly functionalized 4-arylpiperidine
Boice, Geneviève N.,Savarin, Cécile G.,Murry, Jerry A.,Conrad, Karen,Matty, Louis,Corley, Edward G.,Smitrovich, Jacqueline H.,Hughes, Dave
, p. 11367 - 11374 (2007/10/03)
In this manuscript, an efficient synthesis of a functionalized 4-arylpiperidine is disclosed. Several synthetic approaches towards formation of the key aryl-piperidine sp3 carbon-carbon bond are discussed, including a scalable route to the piperidine via
