827624-06-6

Basic information

• Product Name: 1H,3H-Pyrrolo[1,2-c]oxazol-1-one,tetrahydro-3-(1-methylethyl)-(9CI)
• Synonyms: 1H,3H-Pyrrolo[1,2-c]oxazol-1-one,tetrahydro-3-(1-methylethyl)-(9CI)
• CAS NO: 827624-06-6
• Molecular Formula: C9H15NO2
• Molecular Weight: 169.2209
• Product Categories: PYRROLE
• Mol File: 827624-06-6.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1H,3H-Pyrrolo[1,2-c]oxazol-1-one,tetrahydro-3-(1-methylethyl)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H,3H-Pyrrolo[1,2-c]oxazol-1-one,tetrahydro-3-(1-methylethyl)-(9CI)(827624-06-6)
• EPA Substance Registry System: 1H,3H-Pyrrolo[1,2-c]oxazol-1-one,tetrahydro-3-(1-methylethyl)-(9CI)(827624-06-6)

Safety Data

• Hazardous Substances Data: 827624-06-6(Hazardous Substances Data)

Upstream product

• 78-84-2 isobutyraldehyde 
• 147-85-3 L-proline 

Relevant articles and documents

The elusive enamine intermediate in proline-catalyzed aldol reactions: NMR detection, formation pathway, and stabilization trends

The missing link: The elusive enamine intermediate of nucleophilic proline catalysis was detected and stereochemically characterized by NMR analysis of the aldehyde self-aldolization reaction in dipolar aprotic solvents. NMR exchange spectroscopy (EXSY) w

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Reactions of aliphatic branched aldehydes with proline in dimethyl sulfoxide or acetonitrile solution afford oxazolidin-5-ones with high diastereoselection.Linear aldehydes afford aldolic/crotonic condensation products; with short reaction times, the presence of oxazolidinones can be detected in the pmr spectra.Acyclic aminoacids and branched aldehydes yield a reaction mixture the pmr and ir spectra of which give evidence for iminic-oxazolidinone equilibria.The structure of (2R,5S)-2-trichloromethyl-1-aza-3-oxabicyclooctan-4-one has been confirmed by X-ray diffraction analysis.