828270-66-2

Basic information

• Product Name: 4-Fluoro-2-(Methylsulfonyl)toluene
• Synonyms: 4-Fluoro-2-(Methylsulfonyl)toluene;4-fluoro-1-methyl-2-(methylsulfonyl)benzene
• CAS NO: 828270-66-2
• Molecular Formula: C₈H₉FO₂S
• Molecular Weight: 188.2192632
• Mol File: 828270-66-2.mol

Chemical Properties

• Boiling Point: 323.3±42.0 °C(Predicted)
• Appearance: /
• Density: 1.240±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 4-Fluoro-2-(Methylsulfonyl)toluene(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Fluoro-2-(Methylsulfonyl)toluene(828270-66-2)
• EPA Substance Registry System: 4-Fluoro-2-(Methylsulfonyl)toluene(828270-66-2)

Safety Data

• Hazardous Substances Data: 828270-66-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
4-Fluoro-2-(Methylsulfonyl)toluene is used as a key intermediate in the synthesis of various pharmaceuticals. Its unique structure and functional groups contribute to the development of new drugs with improved therapeutic properties and efficacy.
Used in Agrochemical Industry:
In the agrochemical sector, 4-Fluoro-2-(Methylsulfonyl)toluene serves as a crucial building block for the production of agrochemicals. Its incorporation into these compounds enhances their performance in crop protection and pest management, ensuring increased agricultural productivity.
Used in Fine Chemicals Industry:
4-Fluoro-2-(Methylsulfonyl)toluene is employed in the synthesis of various fine chemicals, which are high-purity, specialty chemicals used in a wide range of applications, including fragrances, dyes, and coatings. Its presence in these compounds imparts specific properties and improves their performance.
Used in Research and Development:
4-Fluoro-2-(Methylsulfonyl)toluene is utilized as a valuable building block in research and development activities. It aids in the creation of new materials and chemical compounds, driving innovation and advancements in various scientific fields.

Upstream product

• 352-32-9 p-fluorotoluene 
• 124-63-0 methanesulfonyl chloride 
• 445-05-6 5-fluoro-2-methylbenzenesulfonyl chloride 
• 74-88-4 methyl iodide 

Downstream Products

• 1020735-40-3 4-{3-[4-methyl-3-(methylsulfonyl)phenoxy]phenyl}-8-(trifluoromethyl)quinoline 

Relevant articles and documents

Integrase inhibitor compounds

Tricyclic compounds, protected intermediates thereof, and methods for inhibition of HIV-integrase are disclosed.

Total Synergistic effect between triflic acid and bismuth(IIIr antimony(III) chlorides in catalysis of the Methanesulfonylation of Arenes

A total synergistic effect between bismuth(III) or antimony(III) chlorides and triflic acid has been observed in the Friedel-Crafts methanesulfonylation of arenes and has resulted in the development of the first efficient catalytic systems usable for the methanesulfonylation of both activated and deactivated arenes. A proposed mechanism to explain the observed effects is also discussed. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004.