837364-88-2 Usage
Uses
Used in Pharmaceutical Industry:
2,4-Difluoro-3-iodo-pyridine is used as a synthetic intermediate for the development of pharmaceutical drugs. Its unique structure and reactivity make it a valuable component in the creation of new medications, particularly those targeting specific diseases or conditions.
Used in Agrochemical Industry:
In the agrochemical sector, 2,4-Difluoro-3-iodo-pyridine serves as a crucial building block in the synthesis of pesticides and herbicides. Its incorporation into these products enhances their effectiveness in controlling pests and unwanted plant growth, thereby contributing to improved crop yields and agricultural productivity.
Used in Organic Synthesis:
2,4-Difluoro-3-iodo-pyridine is employed as a reactant in organic synthesis, where its unique properties allow for the formation of new compounds with potential applications in various fields. Its versatility makes it a valuable asset in the development of novel organic materials.
Used in Chemical Research:
2,4-DIFLUORO-3-IODO-PYRIDINE is also utilized in chemical research to explore its reactivity and potential applications. Studies on 2,4-Difluoro-3-iodo-pyridine contribute to the advancement of chemical knowledge and may lead to the discovery of new reactions or applications for this compound.
Check Digit Verification of cas no
The CAS Registry Mumber 837364-88-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,3,7,3,6 and 4 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 837364-88:
(8*8)+(7*3)+(6*7)+(5*3)+(4*6)+(3*4)+(2*8)+(1*8)=202
202 % 10 = 2
So 837364-88-2 is a valid CAS Registry Number.
837364-88-2Relevant articles and documents
Regiochemically flexible substitutions of di-, tri-, and tetrahalopyridines: The trialkylsilyl trick
Schlosser, Manfred,Bobbio, Carla,Rausis, Thierry
, p. 2494 - 2502 (2007/10/03)
(Chemical Equation Presented) 2,4-Difluoropyridine, 2,4-dichloropyridine, 2,4,6-trifluoropyridine, 2,4,6-trichloropyridine and 2,3,4,6-tetrafluoropyridine react with standard nucleophiles exclusively at the 4-position under halogen displacement. However, the regioselectivity can be completely reversed if a trialkylsilyl group is introduced in the 5-position of the 2,4-dihalopyridines or in the 3-position of the 2,4,6-trihalopyridines or 2,3,4,6-tetrahalopyridine. Then only the halogen most remote from the bulky silyl unit (at the 2-position in the case of the 2,4-halopyridines, at the 6-position with the other substrates) gets involved in the exchange process. After removal of the silyl protective group the nucleophile is invariably found to occupy the nitrogen-neighboring position.
Rerouting nucleophilic substitution from the 4-position to the 2- or 6-position of 2,4-dihalopyridines and 2,4,6-trihalopyridines: The solution to a long-standing problem
Schlosser, Manfred,Rausis, Thierry,Bobbio, Carla
, p. 127 - 129 (2007/10/03)
(Chemical Equation Presented) 2,4-Difluoro-, 2,4,6-trifluoro-, and 2,3,4,6-tetrafluoropyridine undergo nucleophilic substitution preferentially if not exclusively at the 4-position. However, after the introduction of a trialkylsilyl group at C-3 or C-5, t
