85003-76-5Relevant articles and documents
Inhibition of inducible nitric oxide synthase by acetamidine derivatives of hetero-substituted lysine and homolysine
Young, Robert J.,Beams, Richard M.,Carter, Keith,Clark, Helen A.R.,Coe, Diane M.,Chambers, C. Lynn,Davies, P. Ifeyinwa,Dawson, John,Drysdale, Martin J.,Franzman, Karl W.,French, Colin,Hodgson, Simon T.,Hodson, Harold F.,Kleanthous, Savvas,Rider, Peter,Sanders, Daniela,Sawyer, David A.,Scott, Keith J.,Shearer, Barry G.,Stocker, Richard,Smith, Steven,Tackley, Miriam C.,Knowles, Richard G.
, p. 597 - 600 (2007/10/03)
The synthesis and in vitro evaluation of the acetamidine derivatives of hetero-substituted lysine and homolysine analogues have identified potent inhibitors of human nitric oxide synthase enzymes, including examples with marked selectivity for the inducible isoform. (C) 2000 Elsevier Science Ltd. All rights reserved.
PERHYDRO-1,4-THIAZEPIN-5-ONE AND PERHYDRO-1,4-THIAZOCIN-5-ONE DERIVATIVES AS ANTIHYPERTENSIVES
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, (2008/06/13)
There are disclosed perhydro-1,4-thiazepin-5-one and perhydro-1,4-thiazocin-5-one derivatives and related compounds which are useful as angiotensin converting enzyme inhibitors and as antihypertensives.