85116-75-2Relevant articles and documents
Cross-linked heparin coatings and methods
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, (2009/01/24)
A thromboresistant coating for a medical device, method of coating and coated medical device, the coating including an in situ cross-linked co-polymer of a cross-linkable biomolecule, preferably an adsorbable biomolecule such as a heparin activity biomolecule with at least one prosthetic hydrophobic unit, and a multifunctional crosslinking agent, such as a bis-variant of polyethylene glycol, polyethylene oxide, or polyethylene glycol, wherein the crosslinking is by means of covalent complexation through at least two functional groups of the multifunctional crosslinking agent.
Process for the preparation of lactic acid silyl esters
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, (2008/06/13)
Novel lactic acid silyl esters of the formula STR1 in which R represents alkyl or aryl, are obtained by a new process which comprises reacting a lactic acid of the formula STR2 with a chloromethylsilane of the formula STR3 in which R has the meaning indicated above, in the presence of a tertiary amine and, if appropriate, in the presence of an additional diluent, at temperatures between 50° and 120° C.