856062-06-1

Basic information

• Product Name: Benzenesulfonic acid, 4-amino-
• Synonyms: 22484-64-6 (Zinc[2:1] salt);515-74-2 (Hydrochloride salt);Ai3-15414
• CAS NO: 856062-06-1
• Molecular Formula: C6H7NO3S
• Molecular Weight: 173.18968
• Mol File: 856062-06-1.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Benzenesulfonic acid, 4-amino-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenesulfonic acid, 4-amino-(856062-06-1)
• EPA Substance Registry System: Benzenesulfonic acid, 4-amino-(856062-06-1)

Safety Data

• Hazardous Substances Data: 856062-06-1(Hazardous Substances Data)

Upstream product

• 88-21-1 2-amino-1-benzenesulfonic acid 
• 110-15-6 succinic acid 
• 98-66-8 4-chloro-benzenesulfonic acid 
• 547-58-0 methyl orange 
• 64-19-7 acetic acid 
• 574-69-6 4-(4-hydroxy-[1]naphthylazo)-benzenesulfonic acid 
• 60-29-7 diethyl ether 
• 625-01-4 ethyl chlorosulfate 
• 62-53-3 aniline 
• 305-80-6 4-diazobenzenesulfonic acid 
• 71-43-2 benzene 
• 144-83-2 sulphapyridine 
• 57-67-0 1-amino-4-({[amino(imino)methyl]amino}sulfonyl)benzene 
• 59576-20-4 1-phenyl-2-[4]pyridyl-ethanone-(E)-oxime 

Downstream Products

• 92164-19-7 2-hydroxy-3-[(4-sulfo-phenylimino)-methyl]-benzoic acid 
• 64-17-5 ethanol 
• 927-61-7 1-ethoxy-2-methylpropene 
• 117883-88-2 4-benzotriazol-2-yl-benzenesulfonic acid ; sodium-salt 
• 13846-15-6 N-carbamoyl-sulfanilic acid ; potassium salt 

Relevant articles and documents

Pulse Radiolysis Studies of Aminobenzenesulfonates: Formation of Cation Radicals

Sulfanilic acid and anilinedisulfonic acids (ADS) react with OH radicals (k = 8.2 * 109 and 5.9 * 109 M-1 s-1) to form the corresponding OH adducts.In acid solutions the adducts react with protons to yield cation radicals (k = 5.3 * 108 and 8.7 * 108 M-1 s-1).N3 oxidizes sulfanilic acid directly to the cation radical by an electron-transfer reaction at a diffusion-controlled rate constant, k = 6.5 * 109 M-1 s-1, while the rate of oxidation of ADS by N3 is only 7.6 * 107 M-1 s-1.SO4- on the other hand oxidizes ADS to the cation radicalat a rate of 1.8 * 109 M-1 s-1.Both cation radicals deprotonate to the anilino-type radicals in acid-base equilibria.The pKa of deprotonation of the sulfanilic cation radical is 5.8 +/- 0.05 and that of the ADS cation radical is 4.3 +/- 0.05.

Synthesis and characterization of polyaniline/nickel oxide composites for fuel additive and dyes reduction

Polyaniline (PANI) and Polyaniline/Nickel oxide (PANI/NiO) composites are prepared to use as a potential catalyst, by Chemical oxidation method using ammonium persulfate (NH4)2S2O8)) as an oxidant. Nickel oxide (NiO) nanopartiles are prepared by Sol-gel method. The synthesized products were characterized by Scanning Electron Microscopy (SEM), Energy Dispersive X-ray analysis (EDX), Fourier Transform Infrared Spectroscopy (FTIR) and X-ray Diffraction technique (XRD). The prepared PANI/NiO composites are used as additive with different concentrations in diesel to investigate their efficiency as fuel additive. The catalytic properties are studied by using the synthesized products as catalyst for reduction of dyes in aqueous media. Sodium borohydride (NaBH4) is used as reducing agent. Linear relationships are obtained between time and ln(A0/At) for Methyl orange and Methylene blue. Kapp values were obtained for three catalysts showed the increasing trend of reduction for both dyes as, PANI NiO PANI/NiO composites. Experimental data analysis proved PANI/NiO composites to be efficient catalysts and fuel additive as compared to PANI and NiO.

Cyan color-emitting nitrogen-functionalized carbon nanodots (NFCNDs) from Indigofera tinctoria and their catalytic reduction of organic dyes and fluorescent ink applications

The present study reports the synthesis of nitrogen-functionalized carbon nanodots (NFCNDs) by a low-cost hydrothermal method using the leaf extract of Indigofera tinctoria as a novel carbon precursor. The synthesized NFCNDs were characterized by diverse spectroscopic techniques. The optical properties of N-CNDs were analyzed by UV-visible and fluorescence spectroscopic studies. The quantum yield (QY) for the prepared NFCNDs was found to be 12.6%. The surface morphology, functional groups, and crystallinity of NFCNDs were evaluated by HR-TEM, FT-IR, XRD and Raman spectroscopic methods, respectively. The Raman results revealed the moderate graphite structure of NFCNDs, and the calculated ID/IG value was 0.49. The spherical appearance of the synthesized NFCNDs was confirmed by HR-TEM, and the calculated size of the NFCNDs was 4 nm. The XRD and SAED pattern results gives an evidence for the amorphous nature of the prepared NFCNDs. The thermal stability of NFCNDs was studied by TGA analysis. The resulting NFCNDs acted as a green nanocatalyst and thus efficiently improved the reducing capability of sodium borohydride (NaBH4) in the catalytic reduction of methylene blue (MB) and methyl orange (MO) dyes. Furthermore, the bright cyan emission characteristics of synthesized NFCNDs were utilized as a labeling agent in anti-counterfeiting applications.

Preparation method of p-amino benzene sulfonic acid

The invention discloses a preparation method of p-amino benzene sulfonic acid. The preparation method comprises the following steps: respectively pumping aniline and concentrated sulfuric acid into a mixer provided with a heat exchange device according to a certain proportion, mixing to form salt, feeding the prepared liquid aniline sulfonate into a negative pressure environment, heating, and carrying out transposition dehydration to prepare the p-amino benzene sulfonic acid, wherein the operation cycle of the preparation method is 1.5-3 hours/batch. The p-aminobenzene sulfonic acid provided by the invention exports heat released in the salifying process to obtain liquid-state stable aniline sulfonate, and in the subsequent transposition reaction process, water vapor generated by dehydration is discharged out of the system by utilizing a vacuum negative pressure environment, so that a p-amino benzene sulfonic acid crude product with a good condition is obtained. The preparation method has the characteristics of good production environment, high safety performance, short production period, high yield, complete aniline reaction and the like, and is suitable for popularization and application.

Cornforth and Corey-Suggs reagents as efficient catalysts for sulfonation of aromatic and heteroaromatic compounds using NaHSO3 under solvent free and microwave conditions

Cornforth and Corey-Suggs reagents Pyridinium Dichromate (PDC) and Pyridinium Chlorochromate (PCC) were explored as efficient catalysts for sulfonation of aromatic and heteroaromatic compounds using NaHSO3 in aqueous acetonitrile medium at room temperature within 1–4 h, while microwave assisted reactions took place within 1–4 min under solvent-free conditions. These observations indicate significant rate accelerations in microwave assisted reactions. which were explained due to the bulk activation of molecules induced by insitu generated high temperatures and pressures when microwaves are transmitted through reaction medium.

The performance and degradation mechanism of sulfamethazine from wastewater using IFAS-MBR

Sulfamethazine (SMZ) is an important sulfonamide antibiotic. Although the concentration in the environment is small, it is harmful. The drug residues can be transferred, transformed or accumulated, affecting the growth of animals and plants. In this study, the integrated fixed-film activated sludge membrane bioreactor (IFAS-MBR) were constructed to investigate the performance and degradation mechanism of SMZ. The addition of SMZ had a significant impact on the removal of the chemical oxygen demand (COD) and ammonia nitrogen (NH4 +-N). The optimal operating conditions were hydraulic retention time (HRT) at 10 h and solid retention time (SRT) at 80 d, respectively. On this basis, the effects of different SMZ concentrations on nutrient removal, degradation, and sludge characteristics were compared. The removal efficiency of SMZ increased with the increase of SMZ concentration. The maximum removal rate was as high as 87%. The SMZ dosage also had an obvious effect on sludge characteristics. As the SMZ concentration increased, the extracellular polymer substances (EPS) concentration and the membrane resistance both decreased, which were beneficial for the reduction of membrane fouling. Finally, seven kinds of SMZ biodegradation intermediates were identified, and the possible degradation pathways were speculated. The microbial community results showed that the microbial diversity and richness in the reactor decreased after adding SMZ to the influent. The relative abundance of Bacteroidetes, Actinobacteria, Saccharibacteria and Nitrospirae increased at the phylum level. Sphingobacteria and Betaproteobacteria became dominant species at the class level. The relative abundance of norank-p-Saccharibacteria and Nitrospirae increased significantly, and norank-p-Saccharibacteria may be the dominant bacteria for SMZ degradation.

Novel Biomass-Derived Fe3O4@Pd NPs as Efficient and Sustainable Nanocatalyst for Nitroarene Reduction in Aqueous Media

Abstract: A novel magnetically recyclable nitrogen-doped Fe3O4@Pd NPs was prepared from the biomass-based materials which was employed as carbon and nitrogen source. The as-prepared catalysts were fully characterized by a variety of physicochemical techniques and were exploited for nitroaromatic hydrogenation with broad scope and excellent chemoselectivity using molecular hydrogen as a reductant. The heterogeneous catalysts can be recovered easily and reused for at least eight recycling reactions without obviously loss of catalytic properties. In addition, using this protocol, the key intermediate of marketed drug Osimertinib could be synthesized easily. Graphical Abstract: [Figure not available: see fulltext.].

Effects of water environmental factors on the photocatalytic degradation of sulfamethoxazole by AgI/UiO-66 composite under visible light irradiation

It is necessary to find visible light responsive photocatalysts for rapid and simple degradation of organic pollutants in water environment. In this work, a visible light responsive composite photocatalyst AgI/UiO-66 was prepared by an in situ growth method. Sulfamethoxazole (SMZ) antibiotic was selected as the target contaminant to probe the photocatalytic performance of the as-prepared AgI/UiO-66 composite under visible light irradiation. The results showed that the photocatalytic performance of the AgI/UiO-66 composite enhanced significantly compared to pure AgI. The effects of typical environment factors (i.e. pH, inorganic salt ions and common anions) on the degradation of SMZ were evaluated extensively. Results showed that the investigated pH (5.2, 7.0, 9.5) had no apparent effect on the photocatalytic degradation of SMZ except pH 2.5, at which the degradation rate of SMZ decreased significantly. In addition, inorganic salt ions and Cl?, HCO3? and SO42? anions in water exhibited no apparent effect on the degradation of SMZ. The effect of water matrix on the degradation of SMZ was also investigated. In the river water, the removal efficiency of SMZ was reduced compared with the cleaner water matrix. The capture experiments of radicals confirmed that superoxide radicals ([rad]O2?) and hydroxyl radicals ([rad]OH) were the main active species for the photocatalytic degradation of SMZ in the present work. Finally, the tentative degradation pathways of SMZ were proposed based on the intermediates analysis.

Synthesis method of pharmaceutical intermediate p-aminobenzenesulfonic acid

The invention relates to a synthesis method of a pharmaceutical intermediate p-aminobenzenesulfonic acid. The synthesis method mainly comprises: adding 3 mol 4-aminophenol, 4-5 mol 2-sulfonic toluene,and 10-16 g of aluminum chloride powder to a reaction container, heating the solution to a temperature of 90-110 DEG C, carrying out thermal insulation for 80-120 min, cooling the solution to a temperature of 10-15 DEG C, adding 2 L potassium bromide solution, crystallizing, filtering, dissolving the crystal in a potassium carbonate solution, cooling the solution to a temperature of 5-8 DEG C, crystallizing, filtering to obtain a crystal, washing with a potassium bromide solution, washing with a triethylamine solution, washing with a nitromethane solution, dewatering with a dewatering agent,and drying at a temperature of 110-115 DEG C to obtain the finished product p-aminobenzenesulfonic acid.

Facile fabrication of γ-Fe2O3-nanoparticle modified N-doped porous carbon materials for the efficient hydrogenation of nitroaromatic compounds

Novel γ-Fe2O3-nanoparticle (NP) modified N-doped porous carbon materials (γ-Fe2O3/mCN) were prepared by one-pot pyrolysis of a mixture of melamine, polyacrylonitrile, and FeCl3·6H2O at different temperatures. At a pyrolysis temperature of 900 °C, γ-Fe2O3/mCN-900-20 exhibited a high surface area and a N content of 8.47%, caused by the complete pyrolysis of melamine and polyacrylonitrile at 900 °C. The obtained material γ-Fe2O3/mCN-900-20 was used as a cost-effective catalyst for the hydrogenation of nitrobenzene using N2H4·H2O as the reductant under mild reaction conditions. As compared to other catalysts (e.g., noble metal catalysts), γ-Fe2O3/mCN-900-20 exhibited high catalytic performance (TOF of 311.83 h-1, selectivity of 100%). During the catalytic hydrogenation of nitroaromatic compounds with reducible groups, e.g., alcoholic hydroxyl, halogen, and amino groups, an excellent selectivity close to 100% was achieved. Moreover, because the active sites of γ-Fe2O3 has magnetic performance, the catalyst can be easily recovered using a magnet, and reused at least four runs without an obvious activity decrease. Hence, the easily prepared, cost-effective and reusable γ-Fe2O3/mCN catalyst fabricated in this study demonstrates potential for applications in selective reduction of aromatic nitro compounds.