858954-83-3

Basic information

• Product Name: methyl 6-amino-5-chloro-2-cyclopropyl-pyrimidine-4-carboxylate
• Synonyms: 858954-83-3; aminocyclopyrachlor-methyl; T6N CNJ DZ EG FVO2 B- AL3TJ
• CAS NO: 858954-83-3
• Molecular Formula: C₉H₁₀ClN₃O₂
• Molecular Weight: 227.6476
• Mol File: 858954-83-3.mol

Chemical Properties

• Boiling Point: 382°C at 760 mmHg
• Flash Point: 184.8°C
• Density: 1.459g/cm³
• Vapor Pressure: 4.89E-06mmHg at 25°C
• Refractive Index: 1.628
• CAS DataBase Reference: methyl 6-amino-5-chloro-2-cyclopropyl-pyrimidine-4-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 6-amino-5-chloro-2-cyclopropyl-pyrimidine-4-carboxylate(858954-83-3)
• EPA Substance Registry System: methyl 6-amino-5-chloro-2-cyclopropyl-pyrimidine-4-carboxylate(858954-83-3)

Safety Data

• Hazardous Substances Data: 858954-83-3(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 858954-79-7 ethyl 6-amino-5-chloro-2-cyclopropyl-4-pyrimidinecarboxylate 
• 124-41-4 sodium methylate 
• 858956-08-8 6-amino-5-chloro-2-cyclopropyl-4-pyrimidinecarboxylic acid 
• 616-38-6 carbonic acid dimethyl ester 
• 74-83-9 methyl bromide 
• 1165931-72-5 2-cyclopropyl-4,5-dichloro-6-methoxycarbonylpyrimidine 

Relevant articles and documents

PYRIMIDINE DERIVATIVES AND THEIR USE AS HERBICIDES

The present invention relates to substituted pyrimidine derivatives, as well as N- oxides thereof and agriculturally acceptable salts thereof, and their use to control undesired plant growth, in particular in crops of useful plants. The invention extends to herbicidal compositions comprising such compounds, N-oxides and/or salts as well as mixtures of the same with one or more further active ingredient (such as, for example, an herbicide, fungicide, insecticide and/or plant growth regulator) and/or a safener. The invention further relates to intermediates useful in the preparation of such compounds, and to processes for their preparation.

METHOD FOR PREPARATION OF OPTIONALLY 2-SUBSTITUTED 1,6-DIHYDRO-6-OXO-4-PYRIMIDINECARBOXYLIC ACIDS

A new method for the preparation of optionally 2-substituted 1,6-dihydro-6-oxo-4 pyrimidinecarboxylic acid compounds of formula (1) is disclosed wherein R1 is H or an optionally substituted carbon moiety. Also disclosed is the method comprising additional steps to prepare optionally substituted 4 pyrimidine-carboxylic acids and esters using the compound of formula (1) as an intermediate.

METHOD FOR PREPARING SUBSTITUTED PYRIMIDINES

Disclosed a method for preparing a ester (Formula I) wherein R1 is cyclopropyl, 4-chlorophenyl or 4-bromophenyl; and R2 is C1-C14 alkyl; comprising contacting acetal (Formula II) with a persulfate oxidant in the presence of a strong sulfur- or phosphorus-containing mineral acid and an oxidation resistant solvent.

HERBICIDAL PYRIMIDINES

Compounds of Formula I, and their N-oxides and agriculturally suitable salts, are disclosed which are useful for controlling undesired vegetation wherein R1 is cyclopropyl optionally substituted with 1-5 R5, isopropyl optionally subs