859850-79-6 Usage
Uses
Used in Pharmaceutical Industry:
(2-Pyrrolidin-1-ylpyrid-3-yl)methylamine is used as a Nav1.8 sodium channel blocker for the development of novel therapeutic agents targeting pain management and other related conditions. Its selective blocking activity against the Nav1.8 sodium channel suggests potential applications in the treatment of neuropathic pain, inflammatory pain, and other pain-related disorders.
Additionally, due to the involvement of Nav1.8 sodium channels in the pathophysiology of certain diseases, (2-Pyrrolidin-1-ylpyrid-3-yl)methylamine may also have potential applications in the treatment of autoimmune diseases, neurodegenerative disorders, and other conditions where Nav1.8 channel modulation could provide therapeutic benefits.
Check Digit Verification of cas no
The CAS Registry Mumber 859850-79-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,9,8,5 and 0 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 859850-79:
(8*8)+(7*5)+(6*9)+(5*8)+(4*5)+(3*0)+(2*7)+(1*9)=236
236 % 10 = 6
So 859850-79-6 is a valid CAS Registry Number.
InChI:InChI=1/C10H15N3/c11-8-9-4-3-5-12-10(9)13-6-1-2-7-13/h3-5H,1-2,6-8,11H2
859850-79-6Relevant articles and documents
P2X7 receptor antagonists and methods of use
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Page/Page column 28, (2010/11/27)
The invention is directed to compounds that are P2X7 antagonist and have the formula (I) or (II) or a pharmaceutically acceptable salt, prodrug, salt of a prodrug or a combination thereof, wherein R1, R2, and R3 /sub
AMINO-TETRAZOLES ANALOGUES AND METHODS OF USE
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, (2010/02/14)
A compound having Formula (I) or Formula (II) is disclosed as an P2X7 antagonist, wherein A, B, C, Y, Y, Z, m, v, R1, R2, R3, R4, and R 5, are as defined in the description. Methods and compositions for treating disease or condition modulated by P2X7 are also disclosed.
