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METHYL-(3-PIPERIDIN-1-YL-PROPYL)-AMINE, also known as MPPP, is a chemical compound with the molecular formula C10H22N2. It belongs to the class of organic compounds known as amines, which are compounds derived from ammonia by replacing one or more of the hydrogen atoms with an organic group. MPPP is commonly used as an intermediate in the synthesis of pharmaceuticals and other organic compounds. It has also been investigated for its potential use as a reagent in chemical research and development. MPPP is a colorless, slightly viscous liquid with a pungent odor and is typically stored and handled under strict safety regulations due to its potential hazards and reactivity with other chemicals.

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  • 86010-41-5 Structure
  • Basic information

    1. Product Name: METHYL-(3-PIPERIDIN-1-YL-PROPYL)-AMINE
    2. Synonyms: AKOS BC-1115;METHYL-(3-PIPERIDIN-1-YL-PROPYL)-AMINE;ASINEX-REAG BAS 08767157;N-METHYL-3-PIPERIDIN-1-YLPROPAN-1-AMINE;N-METHYL-N-(3-PIPERIDIN-1-YLPROPYL)AMINE;N-Methyl-(3-piperidin-1-yl-propyl)amine;N-methyl-3-piperidin-1-ylpropan-1-amine(SALTDATA: FREE);N-Methyl 3-piperidinopropan-1-aMine
    3. CAS NO:86010-41-5
    4. Molecular Formula: C9H20N2
    5. Molecular Weight: 156.27
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 86010-41-5.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 216.1°C at 760 mmHg
    3. Flash Point: 73.1°C
    4. Appearance: /
    5. Density: 0.883g/cm3
    6. Vapor Pressure: 0.143mmHg at 25°C
    7. Refractive Index: 1.463
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: METHYL-(3-PIPERIDIN-1-YL-PROPYL)-AMINE(CAS DataBase Reference)
    11. NIST Chemistry Reference: METHYL-(3-PIPERIDIN-1-YL-PROPYL)-AMINE(86010-41-5)
    12. EPA Substance Registry System: METHYL-(3-PIPERIDIN-1-YL-PROPYL)-AMINE(86010-41-5)
  • Safety Data

    1. Hazard Codes: Xi
    2. Statements: 36
    3. Safety Statements: 26
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: IRRITANT
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 86010-41-5(Hazardous Substances Data)

86010-41-5 Usage

Uses

Used in Pharmaceutical Industry:
METHYL-(3-PIPERIDIN-1-YL-PROPYL)-AMINE is used as an intermediate in the synthesis of pharmaceuticals for its ability to be incorporated into various drug molecules, contributing to the development of new medications.
Used in Chemical Research and Development:
METHYL-(3-PIPERIDIN-1-YL-PROPYL)-AMINE is used as a reagent in chemical research and development for its potential to facilitate the creation of new organic compounds and contribute to scientific advancements in the field.

Check Digit Verification of cas no

The CAS Registry Mumber 86010-41-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,6,0,1 and 0 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 86010-41:
(7*8)+(6*6)+(5*0)+(4*1)+(3*0)+(2*4)+(1*1)=105
105 % 10 = 5
So 86010-41-5 is a valid CAS Registry Number.
InChI:InChI=1/C9H20N2/c1-10-6-5-9-11-7-3-2-4-8-11/h10H,2-9H2,1H3

86010-41-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name METHYL-(3-PIPERIDIN-1-YL-PROPYL)-AMINE

1.2 Other means of identification

Product number -
Other names N-methyl-N-(3-piperidylpropyl)amine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:86010-41-5 SDS

86010-41-5Relevant articles and documents

2-PHENYL-5-AMINO-1,3,4-OXADIAZOLES AND THEIR USE AS NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS

-

Page/Page column 31, (2008/06/13)

The present invention relates to novel oxadiazole derivatives of formula (1) having pharmacological activity, processes for their preparation, compositions containing them and their use in the treatment of neurological, psychiatric disorders and gastrointestinal disorders through modulation of the nicotinic α7 receptor formula (I).

Development of a new class of nonimidazole histamine H3 receptor ligands with combined inhibitory histamine N-methyltransferase activity

Apelt, Joachim,Ligneau, Xavier,Pertz, Heinz H.,Arrang, Jean-Michel,Ganellin, C. Robin,Schwartz, Jean-Charles,Schunack, Walter,Stark, Holger

, p. 1128 - 1141 (2007/10/03)

In search of novel ways to enhance histaminergic neurotransmission in the central nervous system, a new class of nonimidazole histamine H3 receptor ligands were developed that simultaneously possess strong inhibitory activity on the main histamine metabolizing enzyme, histamine N-methyltransferase (HMT). The novel compounds contain an aminoquinoline moiety, which is an important structural feature for HMT inhibitory activity, connected by different spacers to a piperidino group (for H3 receptor antagonism). Variation of the spacer structure provides two different series of compounds. One series, having only an alkylene spacer between the basic centers, led to highly potent HMT inhibitors with moderate to high affinity at human histamine H3 receptors. The second series possesses a p-phenoxypropyl spacer, which may be extended by another alkylene chain. This latter series also showed strong inhibitory activity on HMT, and in most cases, the H3 receptor affinity even surpassed that of the first series. One of the most potent compounds with this dual mode of action is 4-(4-(3-piperidinopropoxy)phenylamino)quinoline (34) (hH3, Ki = 0.09 nM; HMT, IC50 = 51 nM). This class of compounds showed high antagonist potency and good H3 receptor selectivity in functional assays in guinea pig on H1, H2, and H3 receptors. Because of low or missing in vivo activity of two selected compounds, the proof of concept of these valuable pharmacological tools for the supposed superior overall enhancing effect on histaminergic neurotransmission failed to appear hitherto.

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