METHYL-(3-PIPERIDIN-1-YL-PROPYL)-AMINE

Base Information

• Chemical Name: METHYL-(3-PIPERIDIN-1-YL-PROPYL)-AMINE
• CAS No.: 86010-41-5
• Molecular Formula: C9H20N2
• Molecular Weight: 156.271
• Hs Code.: 2933399090
• Mol file: 86010-41-5.mol

Synonyms:methyl[3-(1-piperidinyl)propyl]amine;1-(3-methylamino-propyl)-piperidine;1-(3-(N-methylamino)propyl)piperidine;N-METHYL-N-(3-PIPERIDIN-1-YLPROPYL)AMINE;N-Methyl-(3-piperidin-1-yl-propyl)amine;N-methyl-3-piperidin-1-ylpropan-1-amine(SALTDATA: FREE);N-methyl-3-(piperidin-1-yl)propan-1-amine;N-Methyl 3-piperidinopropan-1-aMine;1-(3-Methylamino-propyl)-piperidin;N-methyl-N-(3-piperidylpropyl)amine;

Chemical Property of METHYL-(3-PIPERIDIN-1-YL-PROPYL)-AMINE

Chemical Property:

• Vapor Pressure: 0.143mmHg at 25°C
• PSA: 15.27000
• LogP: 1.41060

Purity/Quality:

98%min ^*data from raw suppliers

N-methyl-3-piperidin-1-ylpropan-1-amine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of METHYL-(3-PIPERIDIN-1-YL-PROPYL)-AMINE

There total 7 articles about METHYL-(3-PIPERIDIN-1-YL-PROPYL)-AMINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

N-formyl-N-(3-piperidylpropyl)amine (104848-49-9) → N-methyl-3-(piperidin-1-yl)propan-1-amine (86010-41-5)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; for 10h; Heating;

DOI:10.1007/BF00776327

Reference yield:

1-(3-aminopropyl)piperidine (3529-08-6) + di-tert-butyl dicarbonate (24424-99-5) → N-methyl-3-(piperidin-1-yl)propan-1-amine (86010-41-5)

Guidance literature:

1-(3-aminopropyl)piperidine; di-tert-butyl dicarbonate; With triethylamine; In dichloromethane;

With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 - 20 ℃;

With sodium hydroxide; water; In tetrahydrofuran; at 0 ℃;

Reference yield:

piperidine (110-89-4) → N-methyl-3-(piperidin-1-yl)propan-1-amine (86010-41-5)

Guidance literature:

Multi-step reaction with 3 steps

1: KI / acetone / 12 h / Heating

2: SOCl₂ / tetrahydrofuran / 2 h / 50 °C

3: KOH; KI / H₂O / 12 h / Heating

With potassium hydroxide; thionyl chloride; potassium iodide; In tetrahydrofuran; water; acetone;

DOI:10.1021/jm0110845

upstream raw materials:

N-(3-chloropropyl)-piperidine

methylamine

N-formyl-N-(3-piperidylpropyl)amine

methylamine hydrochloride

Downstream raw materials:

(4-indol-3-ylcyclohexyl)methyl(3-piperidylpropyl)amine

2-fluoro-N-(3-(methyloxy)-4-{[2-({[3-(1-piperidinyl)propyl]amino}carbonothioyl)hydrazino]carbonyl}phenyl)benzamide

2-fluoro-N-(3-fluoro-4-{[2-({[3-(1-piperidinyl)propyl]amino}carbonothioyl)hydrazino]carbonyl}phenyl)benzamide

2-fluoro-N-(4-{[2-({[3-(1-piperidinyl)propyl]amino}carbonothioyl)hydrazino]carbonyl}phenyl)benzamide