860624-96-0 Usage
Uses
Used in Organic Synthesis:
Methyl 5-phenyl-1H-indole-7-carboxylate is used as a key intermediate in the synthesis of various organic compounds. Its unique structure allows for the formation of a wide range of derivatives, making it a versatile building block in organic chemistry.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, methyl 5-phenyl-1H-indole-7-carboxylate is used as a starting material for the development of new pharmaceuticals. Its indole core and carboxylate functional group can be modified to create novel drug candidates with potential therapeutic applications.
Used in Pharmaceutical Research:
Methyl 5-phenyl-1H-indole-7-carboxylate is utilized in pharmaceutical research for the investigation of its biological activities and potential therapeutic effects. Its unique structure may contribute to the discovery of new drugs with improved efficacy and safety profiles.
Check Digit Verification of cas no
The CAS Registry Mumber 860624-96-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,0,6,2 and 4 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 860624-96:
(8*8)+(7*6)+(6*0)+(5*6)+(4*2)+(3*4)+(2*9)+(1*6)=180
180 % 10 = 0
So 860624-96-0 is a valid CAS Registry Number.
860624-96-0Relevant articles and documents
3,5-Disubstituted-indole-7-carboxamides as IKKβ Inhibitors: Optimization of Oral Activity via the C3 Substituent
Kerns, Jeffrey K.,Busch-Petersen, Jakob,Fu, Wei,Boehm, Jeffrey C.,Nie, Hong,Muratore, Michael,Bullion, Ann,Lin, Guoliang,Li, Huijie,Davis, Roderick,Lin, Xichen,Lakdawala, Ami S.,Cousins, Rick,Field, Rita,Payne, Jeremy,Miller, David D.,Bamborough, Paul,Christopher, John A.,Baldwin, Ian,Osborn, Ruth R.,Yonchuk, John,Webb, Edward,Rumsey, William L.
supporting information, p. 1164 - 1169 (2018/11/23)
IκB kinase β (IKKβ or IKK2) is a key regulator of nuclear factor kappa B (NF-κB) and has received attention as a therapeutic target. Herein we report on the optimization of a series of 3,5-disubstituted-indole-7-carboxamides for oral activity. In doing so
