ION CHANNEL INHIBITOR COMPOUNDS FOR CANCER TREATMENT
The present invention concerns a compound of following general formula (I): where: either R is an R1 group and R′ is an -A1-Cy1 group, or R is an -A1-Cy1 group and R′ is an R1 group, R1 particularly being H or (C1-C6)alkyl group;A1 being an —NH— radical or —NH—CH2— radical;Cy1 particularly being a phenyl group,A is a fused (hetero)aromatic ring having 5 to 7 atoms, for use for treating cancer.
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Paragraph 0223; 0224
(2021/01/25)
Microwave-accelerated reductive amination between ketones and ammonium acetate
A new procedure for reductive amination between ketones and ammonium acetate has been developed to access a variety of primary amines. This protocol takes advantage of microwave heating to significantly accelerate the reaction and offers a convenient and effective method to access some interesting amines. This new procedure compares favorably to previously reported approaches in terms of practicality, efficiency, and functional group compatibility.
Dong, Li,Aleem, Saadat,Fink, Cynthia A.
experimental part
p. 5210 - 5212
(2010/11/05)
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