865472-04-4Relevant articles and documents
ION CHANNEL INHIBITOR COMPOUNDS FOR CANCER TREATMENT
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Paragraph 0223; 0224, (2021/01/25)
The present invention concerns a compound of following general formula (I): where: either R is an R1 group and R′ is an -A1-Cy1 group, or R is an -A1-Cy1 group and R′ is an R1 group, R1 particularly being H or (C1-C6)alkyl group;A1 being an —NH— radical or —NH—CH2— radical;Cy1 particularly being a phenyl group,A is a fused (hetero)aromatic ring having 5 to 7 atoms, for use for treating cancer.
Microwave-accelerated reductive amination between ketones and ammonium acetate
Dong, Li,Aleem, Saadat,Fink, Cynthia A.
experimental part, p. 5210 - 5212 (2010/11/05)
A new procedure for reductive amination between ketones and ammonium acetate has been developed to access a variety of primary amines. This protocol takes advantage of microwave heating to significantly accelerate the reaction and offers a convenient and effective method to access some interesting amines. This new procedure compares favorably to previously reported approaches in terms of practicality, efficiency, and functional group compatibility.