866807-26-3

Basic information

• Product Name: 3-Amino-6-chloro-pyridine-2-carboxylic acid methyl ester
• Synonyms: 3-Amino-6-chloro-pyridine-2-carboxylic acid methyl ester;Methyl 3-amino-6-chloropicolinate
• CAS NO: 866807-26-3
• Molecular Formula: C7H7ClN2O2
• Molecular Weight: 186.59568
• Mol File: 866807-26-3.mol

Chemical Properties

• Boiling Point: 364.7±37.0 °C(Predicted)
• Appearance: /
• Density: 1.384±0.06 g/cm3(Predicted)
• PKA: -0.07±0.10(Predicted)
• CAS DataBase Reference: 3-Amino-6-chloro-pyridine-2-carboxylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Amino-6-chloro-pyridine-2-carboxylic acid methyl ester(866807-26-3)
• EPA Substance Registry System: 3-Amino-6-chloro-pyridine-2-carboxylic acid methyl ester(866807-26-3)

Safety Data

• Hazardous Substances Data: 866807-26-3(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
3-Amino-6-chloro-pyridine-2-carboxylic acid methyl ester is used as an intermediate in the synthesis of various pharmaceuticals. Its unique structure allows for the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
3-Amino-6-chloro-pyridine-2-carboxylic acid methyl ester is also used as an intermediate in the synthesis of agrochemicals, contributing to the development of new pesticides and other agricultural products.
Used in Organic Synthesis:
As a building block in organic synthesis, 3-Amino-6-chloro-pyridine-2-carboxylic acid methyl ester is used for the preparation of heterocyclic compounds, which are important in various chemical and pharmaceutical applications.
Used in Biological Research:
3-Amino-6-chloro-pyridine-2-carboxylic acid methyl ester exhibits some biological activity, making it a potential candidate for further research in biological applications, such as drug discovery and development.

Upstream product

• 67-56-1 methanol 
• 866807-27-4 3-amino-6-chloro-pyridine-2-carboxylic acid 
• 400777-06-2 6-chloro-2-iodopyridin-3-amine 
• 1073182-88-3 3-amino-6-chloro-2-(2-furanyl) pyridine 
• 5350-93-6 6-Chloro-pyridin-3-ylamine 
• 18107-18-1 diazomethyl-trimethyl-silane 

Downstream Products

• 897360-38-2 6-chloropyrido[3,2-d]pyrimidine-2,4(1H,3H)-dione 
• 1036738-12-1 2,4,6-trichloropyrido[3,2-d]pyrimidine 
• 1073182-90-7 3-amino-4-bromo-6-chloropyridine-2-carboxylic acid 

Relevant articles and documents

N-CYCLOHEXYL-5-(THIAZOL-5-YL)-1H-INDOLE-7-CARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS CD38 INHIBITORS FOR INCREASING NAD+ AND FOR THE TREATMENT OF E.G. MUSCULAR DISORDERS

The present invention is directed to a compound of Formula (I) or a pharmaceutically acceptable salt thereof. Compounds of Formula (I) are CD38 inhibitors, which can be used to treat a disease or condition in a subject that benefits from an increase in NAD+ or to treat a mitochondrial disorder in a subject. Such disease or condition is a muscle structure disorder, a neuronal activation disorder, a muscle fatigue disorder, a muscle mass disorder, a metabolic disease, a cancer, a vascular disease, an ocular vascular disease, a muscular eye disease, or a renal disease. The present description discloses the synthesis and characterisation of exemplary compounds as well as pharmacological data thereof (e.g. pages 30 to 135; examples 1 to 61; table). Such an exemplary compound is e.g. N-((1r,4r)-4-(2-methoxyethoxy) cyclohexyl)-5-(thiazol-5-yl)-1H-indole-7-carboxamide (II).

HETEROCYCLIC HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME

A hydrazide compound represented by the formula (I), an N-oxide thereof or suitable salt thereof: has excellent pesticidal activity.