868592-56-7 Usage
Uses
Used in Neuroscience Research:
2-((5'-(4-hydroxyphenyl)-2,2'-bithiophen-5-yl)Methylene)Malononitrile is used as a fluorescent marker for imaging of amyloid aggregates in the brain. Its ability to selectively bind and label these aggregates allows researchers to study the formation and distribution of amyloid plaques, which are associated with neurodegenerative diseases such as Alzheimer's disease.
Used in Chemical Synthesis:
Due to its distinctive structure and functional groups, 2-((5'-(4-hydroxyphenyl)-2,2'-bithiophen-5-yl)Methylene)Malononitrile can be employed as a building block or intermediate in the synthesis of more complex organic compounds. Its malononitrile and bithiophene moieties can be further modified or reacted with other molecules to create novel compounds with potential applications in various fields.
Used in Material Science:
The fluorescent properties of 2-((5'-(4-hydroxyphenyl)-2,2'-bithiophen-5-yl)Methylene)Malononitrile make it a candidate for the development of new materials with potential applications in optoelectronics, sensors, and imaging technologies. Its incorporation into polymers, coatings, or other materials could lead to the creation of advanced materials with improved performance characteristics.
Used in Pharmaceutical Research:
The unique structure and properties of 2-((5'-(4-hydroxyphenyl)-2,2'-bithiophen-5-yl)Methylene)Malononitrile may also make it a valuable compound in the search for new pharmaceutical agents. Its potential interactions with biological targets and its ability to modulate specific pathways could lead to the discovery of new drugs for the treatment of various diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 868592-56-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,8,5,9 and 2 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 868592-56:
(8*8)+(7*6)+(6*8)+(5*5)+(4*9)+(3*2)+(2*5)+(1*6)=237
237 % 10 = 7
So 868592-56-7 is a valid CAS Registry Number.
868592-56-7Relevant articles and documents
Pd-catalyzed oxidative cross-coupling between two electron rich heteroarenes
He, Chun-Yang,Wang, Zhen,Wu, Cai-Zhi,Qing, Feng-Ling,Zhang, Xingang
, p. 3508 - 3513 (2013/11/19)
The transition-metal-catalyzed oxidative cross-coupling between two coupling partners with similar structure and electronic characteristics remains a challenge owing to difficulty in suppressing undesired homo-couplings. We herein report a Pd-catalyzed oxidative cross-coupling between two thiophenes under mild reaction conditions. This approach can also be extended to furans. Some notable advantages of this reaction lie in its synthetic simplicity with the omission of the toxic stannanes coupling partner and excellent functional-group compatibility. The features of this protocol make it an ideal strategy for the construction of a 2,2′-thiophene-thiophene linkage of interest in electronic and optoelectronic materials.
In vivo optical imaging of amyloid aggregates in brain: Design of fluorescent markers
Nesterov, Evgueni E.,Skoch, Jesse,Hyman, Bradley T.,Klunk, William E.,Bacskai, Brian J.,Swager, Timothy M.
, p. 5452 - 5456 (2007/10/03)
(Figure Presented) Routine diagnostics and studies of Alzheimer's disease might benefit form the noninvasive optical imaging of amyloid-β plaques in the brain. A rational design strategy for in vivo amyloid-imaging agents that enter the brain and selectiv
