869365-89-9 Usage
Uses
Used in Pharmaceutical Industry:
(2-aMino-5-chlorophenyl)(2-fluoro-6-Methoxyphenyl)Methanone is used as a potential pharmaceutical candidate for the development of new drugs. Its unique structural features and functional groups may contribute to its biological activity, making it a promising compound for further research and development in the field of medicinal chemistry.
Used in Medicinal Chemistry Research:
(2-aMino-5-chlorophenyl)(2-fluoro-6-Methoxyphenyl)Methanone is used as a subject of study in medicinal chemistry research to explore its potential biological activity and therapeutic applications. (2-aMino-5-chlorophenyl)(2-fluoro-6-Methoxyphenyl)Methanone's structural features and functional groups may provide insights into its interactions with biological targets, paving the way for the development of new therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 869365-89-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,9,3,6 and 5 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 869365-89:
(8*8)+(7*6)+(6*9)+(5*3)+(4*6)+(3*5)+(2*8)+(1*9)=239
239 % 10 = 9
So 869365-89-9 is a valid CAS Registry Number.
InChI:InChI=1S/C14H11ClFNO2/c1-19-12-4-2-3-10(16)13(12)14(18)9-7-8(15)5-6-11(9)17/h2-7H,17H2,1H3
869365-89-9Relevant articles and documents
MLN8054 and Alisertib (MLN8237): Discovery of Selective Oral Aurora A Inhibitors
Sells, Todd B.,Chau, Ryan,Ecsedy, Jeffrey A.,Gershman, Rachel E.,Hoar, Kara,Huck, Jessica,Janowick, David A.,Kadambi, Vivek J.,Leroy, Patrick J.,Stirling, Matthew,Stroud, Stephen G.,Vos, Tricia J.,Weatherhead, Gabriel S.,Wysong, Deborah R.,Zhang, Mengkun,Balani, Suresh K.,Bolen, Joseph B.,Manfredi, Mark G.,Claiborne, Christopher F.
supporting information, p. 630 - 634 (2015/06/30)
The Aurora kinases are essential for cell mitosis, and the dysregulation of Aurora A and B have been linked to the etiology of human cancers. Investigational agents MLN8054 (8) and alisertib (MLN8237, 10) have been identified as high affinity, selective,
Compounds and methods for inhibiting mitotic progression
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Page/Page column 139, (2008/06/13)
This invention relates to compounds and methods for the treatment of cancer. In particular, the invention provides compounds that inhibit Aurora kinase, pharmaceutical compositions comprising the compounds, and methods of using the compounds for the treat
