869583-76-6

Basic information

• Product Name: 6-Methoxy-2-phenylimidazo[1,2-a]pyridine
• Synonyms: 6-Methoxy-2-phenylimidazo[1,2-a]pyridine;6-Methoxy-2-phenylH-iMidazo[1,2-a]pyridine
• CAS NO: 869583-76-6
• Molecular Formula: C₁₄H₁₂N₂O
• Molecular Weight: 224.25788
• Mol File: 869583-76-6.mol

Chemical Properties

• Appearance: /
• Density: 1.15
• CAS DataBase Reference: 6-Methoxy-2-phenylimidazo[1,2-a]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Methoxy-2-phenylimidazo[1,2-a]pyridine(869583-76-6)
• EPA Substance Registry System: 6-Methoxy-2-phenylimidazo[1,2-a]pyridine(869583-76-6)

Safety Data

• Hazardous Substances Data: 869583-76-6(Hazardous Substances Data)

Usage

Uses

Used in Public Health Awareness:
6-Methoxy-2-phenylimidazo[1,2-a]pyridine is used as a reference compound for public health awareness campaigns to educate consumers about the potential risks associated with consuming well-done and burnt meats and fish. This awareness helps individuals make informed decisions about their dietary choices and cooking methods.
Used in Research and Development:
In the field of research and development, 6-Methoxy-2-phenylimidazo[1,2-a]pyridine serves as a model compound for studying the mechanisms of carcinogenesis and the effects of cooking methods on the formation of harmful substances in food. This research contributes to the development of strategies for minimizing exposure to MIP and other harmful compounds in cooked food products.
Used in Food Safety Regulations:
6-Methoxy-2-phenylimidazo[1,2-a]pyridine is used as a benchmark in food safety regulations to set limits and guidelines for the acceptable levels of carcinogenic compounds in cooked meat and fish products. This helps ensure that food manufacturers adhere to safety standards and minimize the risk of cancer associated with the consumption of these foods.
Used in Cooking Method Innovation:
6-Methoxy-2-phenylimidazo[1,2-a]pyridine is used as a catalyst for the development of alternative cooking methods, such as baking, boiling, or steaming, which can reduce the formation of MIP and other harmful compounds in food. These innovative cooking techniques aim to provide healthier options for consumers while maintaining the taste and quality of cooked meat and fish.

Upstream product

• 4636-16-2 iodoacetophenone 
• 10167-97-2 2-amino-5-methoxypyridine 
• 100-41-4 ethylbenzene 
• 67-56-1 methanol 
• 4044-98-8 6-bromo-2-phenylimidazo[1,2-a]pyridine 
• 1072-97-5 5-bromo-2-pyridylamine 
• 70-11-1 α-bromoacetophenone 

Downstream Products

• 1335061-30-7 ethyl 2-(6-methoxy-2-phenylimidazolo[1,2-a]pyridin-3-yl)acetate 
• 869583-79-9 3-iodo-6-methoxy-2-phenylimidazo[1,2-a]pyridine 
• 1335061-29-4 methyl 3-(6-methoxy-2-phenylimidazo[1,2-a]pyridin-3-yl)propanoate 
• 877382-08-6 3-(6-methoxy-2-phenylimidazo[1,2-a]pyridin-3-yl)propanoic acid 
• 877382-06-4 3-(6-methoxy-2-phenylimidazo[1,2-a]pyridin-3-yl)-N-methylpropanamide 
• 877382-05-3 3-(6-methoxy-2-phenylimidazo[1,2-a]pyridin-3-yl)ethanol 
• 877382-04-2 N-(2-(6-methoxy-2-phenylimidazo[1,2-a]pyridin-3-yl)ethyl)acetamide 
• 1335061-32-9 1-(6-methoxy-2-phenylimidazo[1,2-a]pyridin-3-yl)-N,N,N-trimethyl methanaminium iodide 
• 1335061-33-0 3-[2-acetamido-2,2-di-(ethoxycarbonyl)-ethyl]-6-methoxy-2-phenylimidazoimidazo[1,2-a]pyridine 
• 1335061-34-1 3-[2-acetamido-2-ethoxycarbonylethyl]-6-methoxy-2-phenylimidazoimidazo[1,2-a]pyridine 
• 1335061-35-2 3-[2-acetamido-3-hydroxypropyl]-6-methoxy-2-phenylimidazoimidazo[1,2-a]pyridine 
• 1335061-31-8 3-(N,N-dimethylaminomethyl)-6-methoxy-2-phenylimidazo[1,2-a]pyridine 

Relevant articles and documents

A multi pathway coupled domino strategy: I2/ TBHP-promoted synthesis of imidazopyridines and thiazoles via sp3, sp2 and sp C-H functionalization

I2/TBHP-promoted, one-pot, multi pathway synthesis of imidazopyridines and thiazoles has been achieved through readily available ethylarenes, ethylenearenes and ethynearenes. I2/TBHP as an initiator and oxidant is used to realize the C-H functionalization of this domino reaction. Simple and available starting materials, wide range of functional group tolerance, high potential for drug activity of the products and application in production are the advantageous features of this method.

Electrochemical Oxidative C3 Acyloxylation of Imidazo[1,2- a]pyridines with Hydrogen Evolution

The C3-functionalized imidazo[1,2-a]pyridines are versatile nitrogen-fused heterocycles; however, the methods for the C3 acyloxylation of imidazo[1,2-a]pyridines have never been reported. Herein we demonstrate the electrochemical oxidative C3 acyloxylation of imidazo[1,2-a]pyridines for the first time. Notably, by using electricity, the electrochemical oxidative C3 acyloxylation of imidazo[1,2-a]pyridines was carried out under mild conditions. Moreover, in addition to aromatic carboxylic acids, alkyl carboxylic acids were also competent substrates.

Imidazopyridine compound, pharmaceutical composition containing the same, and preparation method and application thereof (by machine translation)

Specifically discloses a pharmaceutical composition containing the compound and a pharmaceutically acceptable salt or a pharmaceutically acceptable solvate [1,2 - a] of the compound, and the preparation method, comprises the following steps of inhibiting, protein selectivity, drug effect strong STAT3 patent medicine, safety and the like, and the like . is particularly suitable for preventing and, or treating tumor growth and metastasis as well as pharmaceutical composition and pharmaceutical acceptable salt or pharmaceutically acceptable salt or pharmaceutically acceptable solvate of the compound in preparing STAT3 high-expression cell abnormal proliferation, form change and exercise function hyperthyroidism, and other related diseases / and are disclosed in the present invention. (by machine translation)

One-pot NBS-promoted synthesis of imidazoles and thiazoles from ethylarenes in water

A facile and eco-friendly method has been developed for the synthesis of imidazoles and thiazoles from ethylarenes in water. The reaction proceeds via in situ formation of α-bromoketone using NBS as a bromine source as well as an oxidant, followed by trapping with suitable nucleophiles to provide the corresponding products in good yields under metal-free conditions.

Design and synthesis of 2-phenylimidazo[1,2-a]pyridines as a novel class of melatonin receptor ligands

A novel class of imidazo[1,2-a]pyridines as melatonin receptor ligands is designed and synthesized. The affinities of 3-(6-methoxy-2-phenylimidazo[1,2-a] pyridine-3-yl)-N-methyl-propionamide 8, N-[2-(6-methoxy-2-phenylimidazo[1,2-a] pyridine-3-yl)-ethyl]-