869586-30-1Relevant articles and documents
PYRIMIDIN-4(3H)-ONE DERIVATIVES AS TRPV4 ANTAGONISTS
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Paragraph 0368-0369; 0371-0372, (2021/11/06)
This invention relates to pyrimidin-4(3H)-one derivatives that act as modulators of the TRPV4 receptor. The present invention also relates to processes for the preparation of novel pyrimidin-4(3H)-one derivatives and to their use in the treatment of a wide range of diseases, syndromes, and disorders, in particular for the treatment of inflammatory, pain, and urological diseases or disorders.
(BIPHENYL-3-YL)-CARBOXYLIC ACIDS AND DERIVATIVES THEREOF AND THEIR USE IN THERAPY
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Page/Page column 25; 28-29, (2010/02/14)
The present invention relates to compounds having the general formula (I) with the definitions of RI-R3 given below, and/or a salt or ester thereof. Furthermore the invention relates to the use of said compounds as a medicament, pref