872355-63-0

Basic information

• Product Name: METHYL 1H-PYRROLO[3,2-B]PYRIDINE-5-CARBOXYLATE
• Synonyms: METHYL 1H-PYRROLO[3,2-B]PYRIDINE-5-CARBOXYLATE;1H-Pyrrolo[3,2-b]pyridine-5-carboxylic acid methyl ester;4-Azaindole-5-carboxylic acid Methyl ester
• CAS NO: 872355-63-0
• Molecular Formula: C₉H₈N₂O₂
• Molecular Weight: 176.18
• EINECS: 200-258-5
• Mol File: 872355-63-0.mol

Chemical Properties

• Appearance: /
• Density: 1.324
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• CAS DataBase Reference: METHYL 1H-PYRROLO[3,2-B]PYRIDINE-5-CARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 1H-PYRROLO[3,2-B]PYRIDINE-5-CARBOXYLATE(872355-63-0)
• EPA Substance Registry System: METHYL 1H-PYRROLO[3,2-B]PYRIDINE-5-CARBOXYLATE(872355-63-0)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 22
• HazardClass: IRRITANT
• Hazardous Substances Data: 872355-63-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
METHYL 1H-PYRROLO[3,2-B]PYRIDINE-5-CARBOXYLATE is used as a building block for the synthesis of various bioactive molecules and pharmaceutical drugs, contributing to the development of new therapeutic agents.
Used in Cancer Treatment Research:
METHYL 1H-PYRROLO[3,2-B]PYRIDINE-5-CARBOXYLATE is used as a potential therapeutic agent in the treatment of various types of cancer, as it has been studied for its potential applications in this area.
Used in Neurological Disorders Research:
METHYL 1H-PYRROLO[3,2-B]PYRIDINE-5-CARBOXYLATE is used as a potential therapeutic agent in the treatment of neurological disorders, as it has been studied for its potential applications in this field.

Upstream product

• 872355-62-9 5-acetylamino-5-trimethylsilanylethynyl-2-nicotinic acid methyl ester 
• 24242-20-4 5-amino-pyridine-2-carboxylic acid 
• 872355-60-7 methyl 5-amino-6-iodopyridine-2-carboxylate 
• 872355-61-8 5-amino-6-trimethylsilylacetylene-2-nicotinic acid methyl ester 
• 55338-73-3 5-amino-2-cyanopyridine 
• 67515-76-8 methyl 5-amino-2-pyridinecarboxylate 

Downstream Products

• 872355-64-1 1H-pyrrolo[3,2-b]pyridine-5-carboxylic acid 
• 1207608-24-9 C₁₅H₁₁N₃O₄ 
• 1207608-28-3 C₁₅H₁₁N₃O₄ 
• 1254360-91-2 methyl 2,3-dihydro-1H-pyrrolo[3,2-b]pyridine-5-carboxylate 
• 1254360-92-3 1-tert-butyl 5-methyl 2,3-dihydro-1H-pyrrolo[3,2-b]pyridine-1,5-dicarboxylate 
• 1260385-00-9 methyl 1-(benzenesulfonyl)-1H-pyrrolo[3,2-b]pyridine-5-carboxylate 

Relevant articles and documents

Synthesis and antiproliferative activity of pyrrolo[3,2-b]pyridine derivatives against melanoma

Synthesis of a new series of diarylureas and amides having pyrrolo[3,2-b]pyridine scaffold is described. Their in vitro antiproliferative activity against human melanoma cell line A375 and HS 27 human fibroblast cell line was tested and the effect of subs

AZAINDOLE DERIVATIVES AS INHIBITORS OF P38 KINASE

The invention is directed to methods to inhibit p38 kinase, preferably p38-α using compounds which are azaindoles wherein the azaindoles are coupled through an azacyclic linker to another cyclic moiety.