875551-59-0

Basic information

• Product Name: (S)-2-N-Boc-aminomethylmorpholine
• Synonyms: (S)-2-N-Boc-aminomethylmorpholine;(S)-tert-Butyl (Morpholin-2-ylMethyl)carbaMate;(S)-2-(Boc-aMinoMethyl)Morpholine;N-[(2S)-2-Morpholinylmethyl]carbamic acid 1,1-dimethylethyl ester;tert-butyl N-[(2S)-morpholin-2-ylmethyl]carbamate;-tert-Butyl (morpholin-2-ylmethyl)
• CAS NO: 875551-59-0
• Molecular Formula: C₁₀H₂₀N₂O₃
• Molecular Weight: 216.279
• Mol File: 875551-59-0.mol

Chemical Properties

• Boiling Point: 334°C at 760 mmHg
• Flash Point: 155.8°C
• Appearance: /
• Density: 1.032g/cm³
• Vapor Pressure: 0.000131mmHg at 25°C
• Refractive Index: 1.452
• Storage Temp.: 2-8°C(protect from light)
• PKA: 12.22±0.46(Predicted)
• CAS DataBase Reference: (S)-2-N-Boc-aminomethylmorpholine(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-N-Boc-aminomethylmorpholine(875551-59-0)
• EPA Substance Registry System: (S)-2-N-Boc-aminomethylmorpholine(875551-59-0)

Safety Data

• Hazardous Substances Data: 875551-59-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
(S)-2-N-Boc-aminomethylmorpholine is used as a building block in organic synthesis for the creation of biologically active molecules. Its chiral nature and the presence of the N-Boc protecting group make it a versatile component in the development of pharmaceutical compounds.
Used in Organic Synthesis:
(S)-2-N-Boc-aminomethylmorpholine is used as a protecting agent for amine functionalities during chemical reactions. The N-Boc group provides a temporary shield that prevents unwanted side reactions, allowing for cleaner and more controlled synthetic pathways in the preparation of complex organic molecules.
Used in Research and Development:
In the field of research and development, (S)-2-N-Boc-aminomethylmorpholine is utilized for exploring new synthetic routes and methodologies. Its unique properties and reactivity can contribute to the discovery of novel chemical entities and the optimization of existing synthetic processes.

InChI:InChI=1/C10H20N2O3/c1-10(2,3)15-9(13)12-7-8-6-11-4-5-14-8/h8,11H,4-7H2,1-3H3,(H,12,13)/t8-/m0/s1

Upstream product

• 956010-37-0 1,1-dimethylethyl ({(2S)-4-[(3,4-dichlorophenyl)methyl]-2-morpholinyl}methyl)carbamate 
• 956010-38-1 phenylmethyl (2S)-2-[({[(1,1-dimethylethyl)oxy]carbonyl}amino)methyl]-4-morpholinecarboxylate 
• 875551-47-6 1,1-dimethylethyl {[(2R)-4-(phenylmethyl)-2-morpholinyl]methyl}carbamate 

Downstream Products

• 956010-38-1 phenylmethyl (2S)-2-[({[(1,1-dimethylethyl)oxy]carbonyl}amino)methyl]-4-morpholinecarboxylate 
• 911641-00-4 1,1-dimethylethyl ({(2R)-4-[(2-cyanophenyl)sulfonyl]-2-morpholinyl}methyl)carbamate 
• 911641-01-5 2-{[(2R)-2-(aminomethyl)-4-morpholinyl]sulfonyl}benzonitrile hydrochloride 
• 911641-02-6 N₁-({(2R)-4-[(2-cyanophenyl)sulfonyl]-2-morpholinyl}methyl)-N₂-{[(1,1-dimethylethyl)oxy]carbonyl}-L-leucinamide 
• 911641-03-7 N₁-({(2R)-4-[(2-cyanophenyl)sulfonyl]-2-morpholinyl}methyl)-L-leucinamide hydrochloride 

Relevant articles and documents

SUBSTITUTED 1-METHYL-1H-QUINOLIN-2-ONES AND 1-METHYL-1H-1,5-NAPHTHYRIDIN-2-ONES AS ANTIBACTERIALS

Bicyclic nitrogen containing compounds of formula (I) and their use as antibacterials.

NOVEL COMPOUNDS

This invention relates to novel compounds useful in the treatment of diseases associated with TRPV4 channel receptor. More specifically, this invention relates to certain substituted morpholines and piperidines, according to Formula I wherein: X is O or CH2; R1 is optionally substituted C3-7cycloalkyl, C3-6cycloalkyl-C0-6alkyl, optionally substituted C4-7cycloalkenyl, optionally substituted Het-C0-7alkyl, optionally substituted Het-C0-7alkenyl, optionally substituted aryl, optionally substituted heterocycloalkyl, or optionally substituted heteroaryl- R2 is H, branched or optionally substituted C1-6alkyl, C3-6cycloalkyl-C0-6alkyl, Ar-C0-6alkyl, or Het-C0-6alkyl; and R3 is optionally substituted heterocycloalkyl, optionally substituted aryl, or optionally substituted heteroaryl; or pharmaceutically acceptable salts, hydrates, solvates and physiologically functional derivatives thereof.