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Quinoxaline-6-carboxylic acid methoxy-methyl-amide, also known as Methyl 2-methoxy-N-(1-oxoquinoxalin-6-yl) acetimidate, is a chemical compound with the molecular formula C12H12N4O3. It is a derivative of quinoxaline, which is a heterocyclic compound containing a benzene ring fused to a pyrazine ring. This white to off-white solid is primarily used in pharmaceutical research and development, and has potential applications in the synthesis of various bioactive molecules and pharmaceutical compounds. Its chemical structure and properties make it a versatile and valuable building block for the creation of new chemical entities.

875558-38-6

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875558-38-6 Usage

Uses

Used in Pharmaceutical Research and Development:
Quinoxaline-6-carboxylic acid methoxy-methyl-amide is used as a key intermediate in the synthesis of bioactive molecules and pharmaceutical compounds. Its unique structure allows for the development of new drugs with potential therapeutic applications.
Used in Materials Science:
Quinoxaline-6-carboxylic acid methoxy-methyl-amide may also have uses in materials science due to its chemical properties and structure, potentially contributing to the development of new materials with specific characteristics.
Used in Agrochemicals:
Additionally, Quinoxaline-6-carboxylic acid methoxy-methyl-amide may find applications in the agrochemical industry, where it could be utilized in the development of new pesticides or other agricultural chemicals to improve crop protection and yield.

Check Digit Verification of cas no

The CAS Registry Mumber 875558-38-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,5,5,5 and 8 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 875558-38:
(8*8)+(7*7)+(6*5)+(5*5)+(4*5)+(3*8)+(2*3)+(1*8)=226
226 % 10 = 6
So 875558-38-6 is a valid CAS Registry Number.

875558-38-6Relevant articles and documents

ANTI-HCMV COMPOSITIONS AND METHODS

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Page/Page column 25; 33; 35; 37, (2016/06/06)

Novel compounds useful for treating and/or preventing HCMV infections are provided.

CERTAIN CHEMICAL ENTITES, COMPOSITIONS, AND METHODS

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Paragraph 0175, (2013/04/10)

Chemical entities that are kinase inhibitors, pharmaceutical compositions and methods of treatment of cancer are described.

CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS

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Paragraph 0181, (2013/04/13)

Chemical entities that are kinase inhibitors, pharmaceutical compositions and methods of treatment of cancer are described. Specifically quinoxaline derivatives of Formula I and their use in modulating the activity of Braf and/or mutant Braf kinase to reg

CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS

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Paragraph 0195, (2013/03/28)

Chemical entities based on quinoxaline that are kinase inhibitors are described. Specifically quinoxaline derivatives of Formula I, containing a diarylamide or diarylurea substructure that inhibit Braf mutant kinase activity, pharmaceutical compositions c

Certain Chemical Entities, Compositions, and Methods

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Paragraph 0453; 0454; 0455, (2013/03/26)

Chemical entities that are kinase inhibitors, pharmaceutical compositions and methods of using these chemical entities, e.g., for treatment of cancer are described.

Pyrazolone based TGFβR1 kinase inhibitors

Guckian, Kevin,Carter, Mary Beth,Lin, Edward Yin-Shiang,Choi, Michael,Sun, Lihong,Boriack-Sjodin, P. Ann,Chuaqui, Claudio,Lane, Benjamin,Cheung, Kam,Ling, Leona,Lee, Wen-Cherng

scheme or table, p. 326 - 329 (2010/04/05)

Interruption of TGFβ signaling through inhibition of the TGFβR1 kinase domain may prove to have beneficial effect in both fibrotic and oncological diseases. Herein we describe the SAR of a novel series of TGFβR1 kinase inhibitors containing a pyrazolone core. Most TGFβR1 kinase inhibitors described to date contain a core five-membered ring bearing N as H-bond acceptor. Described herein is a novel strategy to replace the core structure with pyrazolone ring, in which the carbonyl group is designed as an H-bond acceptor to interact with catalytic Lys 232.

Substituted Pyrazalones

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Page/Page column 25, (2010/04/23)

The invention is related to compounds of formula (I) as antagonists of the TGFβ family type I receptors, Alk5 and/or AIk 4, compositions and methods of use. The compounds of formula (I) can be employed in the prevention and/or treatment of diseases such a

PHARMACEUTICAL COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF COMPLEX DISEASES AND THEIR DELIVERY BY INSERTABLE MEDICAL DEVICES

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Page/Page column 99-101, (2008/06/13)

The present invention relates to polyphenol-like compounds that are useful for inhibiting VCAM-1 expression, MCP-1 expression and/or SMC proliferation in a mammal. The disclosed compounds are useful for regulating markers of inflammatory conditions, including vascular inflammation, and for treatment and prevention of inflammatory and cardiovascular diseases and related disease states.

SUBSTITUTED PYRAZOLES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE

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Page/Page column 41, (2008/06/13)

The present invention relates to substituted pyrazoles, compositions containing such compounds and methods of treatment. The compounds are glucagon receptor antagonists and thus are useful for treating, preventing or delaying the onset of type 2 diabetes

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