6925-00-4Relevant articles and documents
Triketone compound containing quinoxaline structure, and preparation method and application thereof
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Paragraph 0045-0047; 0052-0054; 0059-0061; 0066-0068, (2020/03/13)
The invention belongs to the technical field of medicine synthesis, and particularly relates to a triketone compound containing a quinoxaline structure, and a preparation method and an application thereof. The quinoxaline-containing triketone compound has a structure represented by general formula (I). The preparation method is mainly characterized in that a compound with a structure represented by formula (II) is contacted in the presence of an alkali and a solvent, and R1, R2, R3 and R4 in the formulas are respectively defined in the description. The quinoxaline-containing triketone compoundhas high herbicidal activity, and especially has an excellent effect of preventing and controlling broadleaf weeds and/or gramineous weeds, and the prevention and control effect is even better than that of some commercial herbicides sold in the market.
Activity of novel quinoxaline-derived chalcones on in vitro glioma cell proliferation
Mielcke, Tania R.,Mascarello, Alessandra,Filippi-Chiela, Eduardo,Zanin, Rafael F.,Lenz, Guido,Leal, Paulo César,Chirardia, Louise D.,Yunes, Rosendo A.,Nunes, Ricardo J.,Battastini, Ana M.O.,Morrone, Fernanda B.,Campos, Maria M.
scheme or table, p. 255 - 264 (2012/03/26)
Gliomas are the most common and devastating tumors of the central nervous system (CNS). Many pieces of evidence point out the relevance of natural compounds for cancer therapy and prevention, including chalcones. In the present study, eight synthetic quin
NOVEL ANTIMALARIA AGENT CONTAINING HETEROCYCLIC COMPOUND
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Page/Page column 59, (2008/06/13)
Disclosed is an antimalarial agent containing a compound represented by the formula: [wherein A1 represents a 3-pyridyl group that may have a substituent, a 6-quinolyl group that may have a substituent, or the like; X1 represents a group represented by the formula -C(=O)-NH- or the like; E represents a furyl group, a thienyl group or a phenyl group; with the proviso that A1 may have one to three substituents, and E has one of two substituents] or a salt thereof or hydrates thereof.