878805-22-2

Basic information

• Product Name: 3-CYCLOPROPYLPYRIDINE-2-CARBONITRILE
• Synonyms: 3-CYCLOPROPYLPYRIDINE-2-CARBONITRILE;3-cyclopropylpicolinonitrile;2-Pyridinecarbonitrile, 3-cyclopropyl-
• CAS NO: 878805-22-2
• Molecular Formula: C9H8N2
• Molecular Weight: 144.17322
• Mol File: 878805-22-2.mol

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 3-CYCLOPROPYLPYRIDINE-2-CARBONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-CYCLOPROPYLPYRIDINE-2-CARBONITRILE(878805-22-2)
• EPA Substance Registry System: 3-CYCLOPROPYLPYRIDINE-2-CARBONITRILE(878805-22-2)

Safety Data

• Hazardous Substances Data: 878805-22-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Synthesis:
3-Cyclopropylpyridine-2-carbonitrile is used as a key intermediate in the synthesis of pharmaceuticals for its ability to contribute to the molecular structures of various drugs. Its unique cyclopropylpyridine framework allows for the development of new therapeutic agents with potential applications in treating a range of diseases.
Used in Agrochemical Synthesis:
In the agrochemical industry, 3-Cyclopropylpyridine-2-carbonitrile is utilized as a building block for the creation of novel agrochemicals. Its incorporation into molecular structures can lead to the development of more effective pesticides, herbicides, and other agricultural chemicals that can improve crop yields and protect against pests.
Used in Heterocyclic Compound Development:
3-Cyclopropylpyridine-2-carbonitrile has been identified as a potential precursor in the development of heterocyclic compounds for various industrial applications. Its unique structure can be further modified and functionalized to create a wide array of heterocyclic compounds with diverse properties and uses in different industries, such as materials science, chemical engineering, and pharmaceuticals.
Used in Anti-Cancer Research:
3-Cyclopropylpyridine-2-carbonitrile is studied for its biological activities, particularly its potential as an anti-cancer agent. Its unique structure may contribute to the development of new cancer therapies, offering novel treatment options for patients and potentially improving outcomes in cancer treatment. Further research is needed to fully understand its anti-cancer properties and optimize its use in this field.

Upstream product

• 188918-73-2 3-cyclopropylpyridineloxide 
• 7677-24-9 trimethylsilyl cyanide 
• 55758-02-6 3-bromopyridine-2-carbonitrile 
• 411235-57-9 cyclopropylboronic acid 
• 2402-97-3 3-bromopyridine N-oxide 
• 626-55-1 3-Bromopyridine 

Relevant articles and documents

Synthesis method of (3-cyclopropylpyridin-2-yl) methylamine hydrochloride

The invention provides a synthesis method of (3-cyclopropylpyridin-2-yl) methylamine hydrochloride, and belongs to the technical field of synthesis of organic chemical intermediates. The preparation method comprises the following steps: reacting 3-bromo-2-cyanopyridine with cyclopropylboronic acid, a phosphine ligand, an alkali and a catalyst under the protection of nitrogen, then reacting with hydrogen under the action of the catalyst, reacting with di-tert-butyl dicarbonate and alkali, and finally reacting with an organic solvent solution of hydrogen chloride to obtain a target product (3-cyclopropylpyridin-2-yl) methylamine hydrochloride. The 3-bromo-2-cyanopyridine is prepared by taking 3-bromopyridine as a raw material and carrying out nitrogen oxidation and cyanation. The method is reasonable in process design, simple in experimental operation and easy to control.

Synthesis method of (3-cyclopropylpyridin-2-yl) methylamine

The invention belongs to the technical field of medical intermediates, and particularly relates to a synthesis method of (3-cyclopropylpyridin-2-yl) methylamine. The synthesis method of the (3-cyclopropylpyridin-2-yl) methylamine is provided for the first time, a synthesis route is provided for the synthesis method of the (3-cyclopropylpyridin-2-yl) methylamine, the synthesis method of the (3-cyclopropylpyridin-2-yl) methylamine is short in route, reasonable in design, easy to operate and easy to control, and meanwhile the yield of the obtained product is high.

NOVEL SUBSTITUTED IMIDAZOLE DERIVATIVES

The present invention relates to a compound represented by Formula [I] or a pharmaceutically acceptable salt or ester thereof: wherein: X1, X2, X3, and X4, which may be identical or different, are each C or N, provided that none to two of X1, X2, X3, and X4 is/are N; Y is CH or N; R1, R1', R2, R2', R3, R3', R4, and R4', which may be identical or different, are each a hydrogen atom, a lower alkyl group, or the like; R5 is a hydrogen atom or a methyl group; R6 and R7, which may be identical or different, are each a hydrogen atom, a lower alkyl group, or the like; R8 and R8', which may be identical or different, are each a hydrogen atom, a lower alkyl group, or the like; R9 is an aryl group or a heteroaryl group which may be substituted; and n is an integer from 1 to 3, and a PLK1 inhibitor or an anticancer agent containing the same.