878805-97-1

Basic information

• Product Name: 3-(methylsulfonyl)-2-Pyridinamine
• Synonyms: 3-(methylsulfonyl)-2-Pyridinamine;3-(Methylsulfonyl)pyridin-2-amine;2-PYRIDINAMINE, 3-(METHYLSULFONYL)-
• CAS NO: 878805-97-1
• Molecular Formula: C6H8N2O2S
• Molecular Weight: 172.20492
• EINECS: -0
• Mol File: 878805-97-1.mol

Chemical Properties

• Boiling Point: 405.4±45.0 °C(Predicted)
• Appearance: /
• Density: 1.358±0.06 g/cm3(Predicted)
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 2.92±0.36(Predicted)
• CAS DataBase Reference: 3-(methylsulfonyl)-2-Pyridinamine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(methylsulfonyl)-2-Pyridinamine(878805-97-1)
• EPA Substance Registry System: 3-(methylsulfonyl)-2-Pyridinamine(878805-97-1)

Safety Data

• Hazardous Substances Data: 878805-97-1(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Applications:
3-(methylsulfonyl)-2-Pyridinamine is used as a pharmaceutical agent for its potential to inhibit certain enzymes and pathways, which can contribute to the development of new drugs for treating various diseases and conditions.
Used in Agrochemical Applications:
In the agrochemical industry, 3-(methylsulfonyl)-2-Pyridinamine is used as a component in the development of pesticides and other agricultural chemicals, leveraging its enzyme-inhibiting properties to control pests and enhance crop protection.
Used in Industrial Applications:
3-(methylsulfonyl)-2-Pyridinamine is used as a corrosion inhibitor in industrial settings, where its chemical structure provides a means to protect materials from degradation and extend their service life.
Used in Organic Synthesis:
3-(methylsulfonyl)-2-Pyridinamine serves as a building block in the synthesis of other organic compounds, contributing to the creation of new molecules with potential applications in various industries.

Upstream product

• 13534-99-1 2-Amino-3-bromopyridine 
• 2386-57-4 methanesulfonic acid sodium salt 
• 147-85-3 L-proline 
• 70682-09-6 2-chloro-3-methylsulphonyl-pyridine 
• 20277-69-4 sodium methansulfinate 

Relevant articles and documents

Synthesis method and applications of polysubstituted 2-aminopyridine derivative

The invention belongs to the field of organic synthetic chemistry, and relates to a synthetic method and applications of a polysubstituted 2-aminopyridine derivative. According to the method, a 1,2,3-triazine compound and a cyanomethyl compound are used as substrates and are subjected to a one-step cycloaddition reaction under an alkaline condition to obtain a polysubstituted 2-aminopyridine derivative, wherein the reaction does not involve in danger and control reagents and medicines, and a simple, safe, efficient and environment-friendly strategy is provided for synthesizing the polysubstituted 2-aminopyridine derivative. According to the present invention, the obtained product is subjected to further derivatization, such that the active molecule or the drug molecule containing the 2-aminopyridine structure can be synthesized, such as active molecule SC-53606, drug molecule apatinib and nevirapine.

INHIBITORS OF PLASMA KALLIKREIN AND USES THEREOF

The present invention provides compounds and compositions thereof which are useful as inhibitors of plasma kallikrein and which exhibit desirable characteristics for the same.

INDOLIN-2-ONE DERIVATIVES USEFUL IN THE TREATMENT OF CNS DISEASES

The present invention is concerned with indolin-2-one derivatives of general formula (I) wherein A is phenyl or a six membered heteroaryl group, containing one or two N atoms, selected from (II) R1 is S(0)2lower alkyl, S(0)2NR4R

3-SUBSTITUTED PYRAZOLES AND USE AS DLK INHIBITORS

The present invention provides for compounds of Formula (I) and various embodiments thereof, and compositions comprising compounds of Formula (I) and various embodiments thereof. (I) In compounds of Formula I, the groups R1, R2, R3, R4, R5, R6 and R7 have the meaning as described herein. The present invention also provides for methods of using compounds of Formula I and compositions comprising compounds of Formula (I) as DLK inhibitors and for treating neurodegeneration diseases and disorders.

NOVEL SUBSTITUTED IMIDAZOLE DERIVATIVES

The present invention relates to a compound represented by Formula [I] or a pharmaceutically acceptable salt or ester thereof: wherein: X1, X2, X3, and X4, which may be identical or different, are each C or N, provided that none to two of X1, X2, X3, and X4 is/are N; Y is CH or N; R1, R1', R2, R2', R3, R3', R4, and R4', which may be identical or different, are each a hydrogen atom, a lower alkyl group, or the like; R5 is a hydrogen atom or a methyl group; R6 and R7, which may be identical or different, are each a hydrogen atom, a lower alkyl group, or the like; R8 and R8', which may be identical or different, are each a hydrogen atom, a lower alkyl group, or the like; R9 is an aryl group or a heteroaryl group which may be substituted; and n is an integer from 1 to 3, and a PLK1 inhibitor or an anticancer agent containing the same.