885267-41-4

Basic information

• Product Name: 5-BROMOQUINOLINE-8-CARBALDEHYDE
• Synonyms: 5-BROMOQUINOLINE-8-CARBALDEHYDE;8-Quinolinecarboxaldehyde, 5-broMo-;5-Bromo-8-formylquinoline, 5-Bromo-8-formyl-1-azanaphthalene
• CAS NO: 885267-41-4
• Molecular Formula: C₁₀H₆BrNO
• Molecular Weight: 236.06
• Product Categories: Organohalides;Quinoline
• Mol File: 885267-41-4.mol

Chemical Properties

• Boiling Point: 374.6±27.0 °C(Predicted)
• Appearance: /
• Density: 1.632±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 2.37±0.29(Predicted)
• CAS DataBase Reference: 5-BROMOQUINOLINE-8-CARBALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BROMOQUINOLINE-8-CARBALDEHYDE(885267-41-4)
• EPA Substance Registry System: 5-BROMOQUINOLINE-8-CARBALDEHYDE(885267-41-4)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 885267-41-4(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
5-Bromoquinoline-8-carbaldehyde is used as a precursor for the synthesis of various pharmaceutical drugs. It serves as a building block in the production of heterocyclic compounds, which are essential in the development of new medications.
Used in Organic Synthesis:
5-Bromoquinoline-8-carbaldehyde is used as a key intermediate in the synthesis of organic compounds. Its aromatic properties make it a valuable component in the creation of complex organic molecules.
Used in Bioimaging Applications:
5-Bromoquinoline-8-carbaldehyde is used in the development of fluorescent probes for bioimaging. These probes are essential tools in the field of molecular biology and cell biology, allowing researchers to visualize and study biological processes at the molecular level.

Upstream product

• 611-32-5 8-methylquinoline 
• 74316-55-5 5-bromo-8-methyl-quinoline 
• 39478-78-9 5-bromo-2-methylaniline 
• 1309959-33-8 5-bromo-8-(dibromomethyl)quinoline 

Downstream Products

• 1445781-87-2 (S)-5-((1-(3-fluorophenyl)-2-(methylamino)ethyl)amino)quinoline-8-carboxamide 
• 1445781-88-3 (S)-5-{1-(3-fluoro-phenyl)-2-[methyl-(4-nitro-benzenesulfonyl)-amino]-ethylamino}-quinoline-8-carboxylic acid methyl ester 
• 1445781-89-4 (S)-5-{1-(3-fluoro-phenyl)-2-[methyl-(4-nitro-benzenesulfonyl)-amino]-ethylamino}-quinoline-8-carboxamide 
• 1445781-45-2 methyl 5-bromoquinoline-8-carboxylate 
• 1590378-61-2 5-(4-phenylbutyl)-3{8-[(tetrahydro-2H-pyran-2-yloxy)methyl]quinoline-5-yl}-1,2,4-oxadiazole 
• 1590378-65-6 {5-[5-(4-phenylbutyl)-1,2,4-oxadiazol-3-yl]quinoline-8-yl}methanol 
• 1590378-69-0 5-[5-(4-phenylbutyl)-1,2,4-oxadiazol-3-yl]quinoline-8-carbaldehyde 
• 1442660-41-4 (5-bromoquinolin-8-yl)(phenyl)methanone 

Relevant articles and documents

Rhodium(III)-Catalyzed Direct Coupling of Quinoline-8-Carbaldehydes with (Het)Arylboronic Acids for the Synthesis of 8-Aryloylquinolines

Herein, we describe a method for the synthesis of aryl-(het)aryl ketones by Rh(III)-catalyzed direct coupling between quinoline-8-carbaldehydes and (het)arylboronic acids. The method has a broad substrate scope, a high functional group tolerance, and uses

Rh(iii)-Catalyzed straightforward arylation of 8-methyl/formylquinolines using diazo compounds

A straightforward Rh(iii)-catalyzed general strategy was developed for the introduction of naphthol/phenol moieties to the C(sp3)-H bond of 8-methylquinoline using diazonaphthalen-2(1H)-ones/quinone diazides. The developed method was further extended towards the arylation of 8-formylquinolines to accomplish diarylketone derivatives. The method is simple, relatively rapid, and chemo and regioselective with a wide scope and functional group tolerance. The synthetic utility was established through gram-scale synthesis and biologically active molecule construction.

NOVEL HETEROCYCLIC CARBOXAMIDES AS MODULATORS OF KINASE ACTIVITY

The invention provides novel heterocyclic carboxamide compounds compounds according to Formula (I) their manufacture and use for the treatment of hyperproliferative diseases, such as cancer.

INSECTICIDAL COMPOUNDS BASED ON ISOAZOLINE DERIVATIVES

The present invention relates to compounds of formula (I): Wherein A1, A2, A3, A4, G1, L, Y1, Y2, Y3, Y4, R1, R2, R3 and R

INSECTICIDAL COMPOUNDS BASED ON ISOXAZOLINE DERIVATIVES

The present invention relates to compounds of formula (I): Wherein A1, A2, A3, A4, G1, L, Y1, Y2, Y3, Y4, R1, R2, R3 and R