5-Bromoquinoline-8-carbaldehyde

Base Information

Chemical Name:5-Bromoquinoline-8-carbaldehyde
CAS No.:885267-41-4
Molecular Formula:C10H6 Br N O
Molecular Weight:236.068
Hs Code.:2933499090
European Community (EC) Number:689-100-9
DSSTox Substance ID:DTXSID00585983
Wikidata:Q82477997
Mol file:885267-41-4.mol

Synonyms:5-BROMOQUINOLINE-8-CARBALDEHYDE;885267-41-4;5-Bromoquinoline-8-carboxaldehyde;MFCD08064042;8-Quinolinecarboxaldehyde,5-bromo-;5-Bromo-8-formylquinoline;SCHEMBL2011852;5-bromo-8-quinolinecarboxaldehyde;DTXSID00585983;NPLPBRIDHFAGPQ-UHFFFAOYSA-N;AKOS022176087;AB43508;PS-4861;BL005645;SY064853;CS-0155712;EN300-120242;A927912;Z1269195637

Suppliers and Price of 5-Bromoquinoline-8-carbaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-Bromoquinoline-8-carbaldehyde
500mg
$ 110.00

TRC
5-Bromoquinoline-8-carbaldehyde
250mg
$ 75.00

SynQuest Laboratories
5-Bromoquinoline-8-carboxaldehyde
1 g
$ 52.00

SynQuest Laboratories
5-Bromoquinoline-8-carboxaldehyde
5 g
$ 192.00

Matrix Scientific
5-Bromoquinoline-8-carbaldehyde
10g
$ 690.00

Matrix Scientific
5-Bromoquinoline-8-carbaldehyde
5g
$ 514.00

Matrix Scientific
5-Bromoquinoline-8-carbaldehyde
25g
$ 1380.00

Frontier Specialty Chemicals
5-Bromoquinoline-8-carboxaldehyde 97%
5g
$ 150.00

Frontier Specialty Chemicals
5-Bromoquinoline-8-carboxaldehyde 97%
1g
$ 40.00

Crysdot
5-Bromoquinoline-8-carbaldehyde 95+%
5g
$ 339.00

Total 22 raw suppliers

Chemical Property of 5-Bromoquinoline-8-carbaldehyde

Chemical Property:

Boiling Point:374.6±27.0 °C(Predicted)
PKA:2.37±0.29(Predicted)
PSA：29.96000
Density:1.632±0.06 g/cm3(Predicted)
LogP:2.80980
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
XLogP3:2.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:234.96328
Heavy Atom Count:13
Complexity:197

Purity/Quality:

99%, ^*data from raw suppliers

5-Bromoquinoline-8-carbaldehyde ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(C=CC(=C2N=C1)C=O)Br

Technology Process of 5-Bromoquinoline-8-carbaldehyde

There total 4 articles about 5-Bromoquinoline-8-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 74316-55-5
5-bromo-8-methyl-quinoline

: 885267-41-4
5-bromoquinoline-8-carboaldehyde

Guidance literature:: 5-bromo-8-methyl-quinoline; With N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); In 1,2-dichloro-ethane; for 5h; Reflux;

In water; for 5h; Reflux;
DOI:10.1021/acs.joc.0c01490

Reference yield:

: 1309959-33-8
5-bromo-8-(dibromomethyl)quinoline

: 885267-41-4
5-bromoquinoline-8-carboaldehyde

Guidance literature:: With water; silver nitrate; In acetone; at 20 ℃; for 5h; Darkness;

Reference yield:

: 39478-78-9
5-bromo-2-methylaniline

: 885267-41-4
5-bromoquinoline-8-carboaldehyde

Guidance literature:: Multi-step reaction with 3 steps

1.1: sulfuric acid; nitrobenzene / water / 3 h / 150 °C

1.2: 0 °C

2.1: N-Bromosuccinimide; dibenzoyl peroxide / tetrachloromethane / 12 h / Reflux

3.1: water; silver nitrate / acetone / 5 h / 20 °C / Darkness

With N-Bromosuccinimide; sulfuric acid; water; silver nitrate; nitrobenzene; dibenzoyl peroxide; In tetrachloromethane; water; acetone;