887707-33-7

Basic information

• Product Name: 5-(CHLOROMETHYL)-2-METHOXY-3-(TRIFLUOROMETHYL)-PYRIDINE
• Synonyms: 5-(CHLOROMETHYL)-2-METHOXY-3-(TRIFLUOROMETHYL)-PYRIDINE;Pyridine, 5-(chloroMethyl)-2-Methoxy-3-(trifluoroMethyl)-
• CAS NO: 887707-33-7
• Molecular Formula: C8H7ClF3NO
• Molecular Weight: 230.01
• Mol File: 887707-33-7.mol

Chemical Properties

• Boiling Point: 250.1±35.0 °C(Predicted)
• Appearance: /
• Density: 1.476±0.06 g/cm3(Predicted)
• PKA: -2.56±0.10(Predicted)
• CAS DataBase Reference: 5-(CHLOROMETHYL)-2-METHOXY-3-(TRIFLUOROMETHYL)-PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(CHLOROMETHYL)-2-METHOXY-3-(TRIFLUOROMETHYL)-PYRIDINE(887707-33-7)
• EPA Substance Registry System: 5-(CHLOROMETHYL)-2-METHOXY-3-(TRIFLUOROMETHYL)-PYRIDINE(887707-33-7)

Safety Data

• Hazardous Substances Data: 887707-33-7(Hazardous Substances Data)

Upstream product

• 1206124-61-9 5-(chloromethyl)-2-methoxy-3-(trifluoromethyl)pyridine 
• 65753-47-1 2-chloro-3-trifluoromethyl-pyridine 
• 887707-29-1 5-cyano-2-methoxy-3-trifluoromethylpyridine 
• 887707-23-5 2-hydroxy-3-trifluoromethyl-5-(iodo)pyridine 
• 887707-27-9 5-iodo-2-methoxy-3-(trifluoromethyl)pyridine 
• 22245-83-6 3-(trifluoromethyl)pyridin-2-ol 
• 887707-31-5 2-methoxy-3-trifluoromethyl-5-pyridinemethanol 

Relevant articles and documents

SUBSTITUTED 1,2,3,4- TETRAHYDROCYCLOPENTA[b]INDOL-3-YL) ACETIC ACID DERIVATIVES USEFUL IN THE TREATMENT OF AUTOIMMUNE AND INFLAMMATORY DISORDERS

The present invention relates to certain substituted 1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid derivatives of Formula (Ia) and pharmaceutically acceptable salts thereof, which exhibit useful pharmacological properties, for example, as agonists of the S1P1 receptor. Also provided by the present invention are pharmaceutical compositions containing compounds of the invention, and methods of using the compounds and compositions of the invention in the treatment of S1P1 receptor-associated disorders, for example, psoriasis, rheumatoid arthritis, Crohn's disease, transplant rejection, multiple sclerosis, systemic lupus erythematosus, ulcerative colitis, type I diabetes, acne, microbial infections or diseases and viral infections or diseases.

Methyl, trifluoromethyl, and methoxycarbonyl - Introduction to the fifth position on the pyridine ring of chloronicotinyl insecticide imidacloprid

Imidacloprid is the first chloronicotinyl insecticide and is currently the largest-selling insecticide worldwide. As a project to find its variants of different insecticidal spectra, derivatives substituted with methyl, trifluoromethyl, and methoxy-carbonyl at the fifth position on the pyridine ring of imidacloprid were prepared. Copyright Taylor & Francis Group, LLC.