88978-20-5 Usage
Uses
Used in Organic Synthesis:
3-(2,2,2-TRIFLUOROACETAMIDO)BENZENEBORONIC ACID is used as a building block in organic synthesis for its ability to participate in various chemical reactions, facilitating the creation of complex organic molecules.
Used in Pharmaceutical Preparation:
In the pharmaceutical industry, 3-(2,2,2-TRIFLUOROACETAMIDO)BENZENEBORONIC ACID is used as a reagent in the preparation of pharmaceuticals and other biologically active compounds, leveraging its reactivity and complex-forming properties to enhance drug development.
Used in the Development of Selective Sensors:
3-(2,2,2-TRIFLUOROACETAMIDO)BENZENEBORONIC ACID is used as a component in the development of selective sensors due to its capacity to form stable complexes with diols, which is crucial for detecting and measuring specific biological targets.
Used in Drug Delivery Systems:
In drug delivery, 3-(2,2,2-TRIFLUOROACETAMIDO)BENZENEBORONIC ACID is utilized to improve the delivery and targeting of pharmaceuticals, taking advantage of its complex-forming ability to enhance the bioavailability and therapeutic efficacy of drugs.
Check Digit Verification of cas no
The CAS Registry Mumber 88978-20-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,8,9,7 and 8 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 88978-20:
(7*8)+(6*8)+(5*9)+(4*7)+(3*8)+(2*2)+(1*0)=205
205 % 10 = 5
So 88978-20-5 is a valid CAS Registry Number.
InChI:InChI=1/C8H7BF3NO3/c10-8(11,12)7(14)13-6-3-1-2-5(4-6)9(15)16/h1-4,15-16H,(H,13,14)
88978-20-5Relevant articles and documents
Synthesis of diverse β-quaternary ketones via palladium-catalyzed asymmetric conjugate addition of arylboronic acids to cyclic enones
Holder, Jeffrey C.,Goodman, Emmett D.,Kikushima, Kotaro,Gatti, Michele,Marziale, Alexander N.,Stoltz, Brian M.
, p. 5781 - 5792 (2015/08/03)
Abstract The development and optimization of a palladium-catalyzed asymmetric conjugate addition of arylboronic acids to cyclic enone conjugate acceptors is described. These reactions employ air-stable and readily-available reagents in an operationally si
Palladium-catalyzed asymmetric conjugate addition of arylboronic acids to heterocyclic acceptors
Holder, Jeffrey C.,Marziale, Alexander N.,Gatti, Michele,Mao, Bin,Stoltz, Brian M.
supporting information, p. 74 - 77 (2013/02/25)
Flava Flavanone: Asymmetric conjugate additions to chromones and 4-quinolones are reported utilizing a single catalyst system formed in situ from Pd(OCOCF3)2 and (S)-tBuPyOX. Notably, these reactions are performed in wet solvent under ambient atmosphere, and employ readily available arylboronic acids as the nucleophile, thus providing ready access to these asymmetric heterocycles (see scheme).
