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5-cyclopropylpyridin-2-amine is a chemical compound that belongs to the class of amines and pyridine derivatives. It is characterized by a cyclopropyl group attached to a pyridine ring, which endows it with unique structural and chemical properties. 5-cyclopropylpyridin-2-amine is commonly utilized in medicinal and pharmaceutical research due to its potential biological and therapeutic activities, making it a valuable building block for the synthesis of various bioactive compounds. Its unique chemical properties also make it a promising candidate for the development of new materials or as a reagent in organic synthesis.

893738-68-6

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893738-68-6 Usage

Uses

Used in Pharmaceutical Research:
5-cyclopropylpyridin-2-amine is used as a key intermediate in the synthesis of new drugs for targeting specific receptors or enzymes. Its unique structural features allow for the development of compounds with novel mechanisms of action, potentially leading to more effective treatments for various diseases.
Used in Medicinal Chemistry:
As a pyridine derivative, 5-cyclopropylpyridin-2-amine is used as a building block in the design and synthesis of bioactive molecules. Its presence in a molecule can influence the pharmacokinetic and pharmacodynamic properties, making it an important component in the creation of new therapeutic agents.
Used in Organic Synthesis:
5-cyclopropylpyridin-2-amine is utilized as a reagent in organic synthesis, where its unique chemical properties can be harnessed to facilitate specific reactions or to improve the yield and selectivity of synthetic processes.
Used in Material Science:
5-cyclopropylpyridin-2-amine's unique structural and chemical properties make it a potential candidate for the development of new materials with specialized properties, such as improved stability, reactivity, or selectivity in various applications.

Check Digit Verification of cas no

The CAS Registry Mumber 893738-68-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,9,3,7,3 and 8 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 893738-68:
(8*8)+(7*9)+(6*3)+(5*7)+(4*3)+(3*8)+(2*6)+(1*8)=236
236 % 10 = 6
So 893738-68-6 is a valid CAS Registry Number.

893738-68-6Relevant articles and documents

HETEROARYL PLASMA KALLIKREIN INHIBITORS

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Paragraph 0179; 0189; 0196; 0209, (2021/03/19)

The present invention provides compounds and compositions thereof which are useful as inhibitors of plasma kallikrein and which exhibit desirable characteristics for the same.

PLASMA KALLIKREIN INHIBITORS AND USES THEREOF

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Paragraph 0237; 0238; 0296; 0297; 0544; 0586, (2021/03/19)

The present invention provides compounds and compositions thereof which are useful as inhibitors of plasma kallikrein and which exhibit desirable characteristics for the same.

SOLID FORMS OF INHIBITORS OF PLASMA KALLIKREIN

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Paragraph 0091-0092, (2021/10/22)

The present invention provides compounds and compositions thereof which are useful as inhibitors of Plasma Kallikrein (pKal) and which exhibit desirable characteristics for the same.

FORMS AND COMPOSITIONS OF INHIBITORS OF PLASMA KALLIKREIN

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Paragraph 0247, (2021/10/22)

The present invention provides solid forms of compound (1) and compositions thereof which are useful as inhibitors of Plasma Kallikrein (pKal) and which exhibit desirable characteristics for the same.

COMPOUNDS FOR USE IN TREATING NEUROLOGICAL DISORDERS

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Paragraph 00130-00131, (2021/02/05)

Provided are methods for treating neurological disorders using compounds of Formula (I), and pharmaceutically acceptable salts and compositions thereof.

INHIBITORS OF PLASMA KALLIKREIN AND USES THEREOF

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, (2019/09/30)

The present invention provides compounds and compositions thereof which are useful as inhibitors of plasma kallikrein and which exhibit desirable characteristics for the same.

P300/CBP HAT INHIBITORS

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Paragraph 00100; 00146-00147, (2019/09/04)

Provided are compounds of Formula (I): and pharmaceutically acceptable salts and compositions thereof, which are useful for treating a variety of conditions associated with histone acetyltransferase (HAT).

TYK2 INHIBITORS AND USES THEREOF

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Paragraph 00567; 00568, (2018/04/27)

The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of TYK2, and the treatment of TYK2-mediated disorders.

NOVEL BICYCLIC HETEROCYCLIC COMPOUND

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Paragraph 0586; 0587, (2018/09/27)

Provided are a novel compound having a superior inhibitory action on KAT-II, a production method thereof, use thereof, and a pharmaceutical composition containing the aforementioned compound and the like. A compound represented by the formula (I) or a pharmacologically acceptable salt thereof. wherein each symbol is as defined in the DESCRIPTION.

Synthesis of bromocyclopropylpyridines via the Sandmeyer reaction

Striela, Romualdas,Urbelis, Gintaras,Sūd?ius, Jurgis,Ston?ius, Sigitas,Sadzevi?ien?, Rita,Labanauskas, Linas

supporting information, p. 1681 - 1683 (2017/04/06)

The reactions of 2-amino-5-cyclopropylpyridine with organic nitrites in the presence of copper(II) halides in various organic solvents were investigated. Optimal reaction conditions for the Sandmeyer reaction were developed and successfully applied to the synthesis of useful building blocks, bromo and chlorocyclopropylpyridines. Aminocyclopropylpyridines were synthesized in high yields from the corresponding aminobromopyridines under standard Suzuki coupling conditions.

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